Results 71 to 80 of about 2,427,282 (299)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Cyclic Permutations in Determining Crossing Numbers
Discussiones Mathematicae Graph Theory, 2022 The crossing number of a graph G is the minimum number of edge crossings over all drawings of G in the plane. Recently, the crossing numbers of join products of two graphs have been studied.
Klešč Marián, Staš Michal
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Isoperimetric Constants of Infinite Plane Graphs [PDF]
Discrete & Computational Geometry, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lawrencenko, Serge +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Efficient Embedding of Scale-Free Graphs in the Hyperbolic Plane
IEEE/ACM Transactions on Networking, 2018 Hyperbolic geometry appears to be intrinsic in many large real networks. We construct and implement a new maximum likelihood estimation algorithm that embeds scale-free graphs in the hyperbolic space.
Thomas Bläsius +3 more
semanticscholar +1 more source
Plane elementary bipartite graphs
Discrete Applied Mathematics, 2000 A connected graph is elementary if the union of all perfect matchings induces a connected subgraph. It is well known that a connected bipartite graph is elementary if and only if it is \(1\)-extendable, i.e., each edge is contained in a perfect matching. In this paper the authors mainly study properties of plane elementary bipartite graphs.
Zhang, HP, Zhang, FJ
openaire +3 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
3-Facial Coloring of Plane Graphs [PDF]
SIAM Journal on Discrete Mathematics, 2008 A plane graph is l-facially k-colourable if its vertices can be coloured with k colours such that any two distinct vertices on a facial segment of length at most l are coloured differently. We prove that every plane graph is 3-facially 11-colourable.
Havet, Frédéric +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source