Results 31 to 40 of about 135,181 (264)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Acoustic Scattering Analysis of Underwater Elastic Spherical Shell under Point Sound Source Incidence

水下无人系统学报, 2023
In order to study the acoustic scattering of underwater targets, the conversion factor of plane wave and spherical wave of point sound source was calculated on the basis of the analytical solution of the classical Rayleigh normal series, combined with ...
Jinyan ZHENG, Meixia CHEN, Wenkai DONG
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Efficient Transmit Delay Calculation in Ultrasound Coherent Plane-Wave Compound Imaging for Curved Array Transducers

Applied Sciences, 2019
The recently introduced plane-wave compounding method based on multiple plane-wave excitation has enabled several new applications due to its high frame rate (>1000 Hz).
Dooyoung Go, Jinbum Kang, Ilseob Song, Yangmo Yoo   +3 more
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Consideration of Oblique Incidence in 3-D Imaging of a Planar Interface With a Circular Dipole Array in an Air-Filled Borehole

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2020
We consider the effects of oblique incidence of a wave on the creation of a 3-D image of a planar interface with an array-type directional borehole radar. In this study, we focus on the situation where the radar probe is close to the planar interface. In
Satoshi Ebihara, Shyuhei Kotani, Kengo Fujiwara, Yuta Kimura, Takaaki Shimomura, Ryota Uchimura   +5 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

A Low-Profile Transmissive Metasurface for Transformation of Plane Wave to Contour Beam Pattern Using 4-Arm Spiral Element

IEEE Access, 2021
A low-profile transmissive metasurface is proposed to synthesize contour beam pattern for a European region. A slot array feed is used to illuminate same size metasurface aperture with a plane wave at a near field distance of 24 mm.
Abdul Aziz, Fan Yang, Shenheng Xu, Maokun Li   +3 more
doaj   +1 more source