Results 61 to 70 of about 297,354 (275)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Fourier Transform Holography: A Lensless Imaging Technique, Its Principles and Applications

open access: yesPhotonics, 2023
Fourier transform holography (FTH) is a lensless imaging technique where the wave scattered by an object is superimposed with the wave scattered by a reference source positioned in the same plane.
Sara Mustafi, Tatiana Latychevskaia
doaj   +1 more source

Plane-Wave Imaging Challenge in Medical Ultrasound [PDF]

open access: yes2016 IEEE International Ultrasonics Symposium (IUS), 2016
Plane-Wave imaging enables very high frame rates, up to several thousand frames per second. Unfortunately the lack of transmit focusing leads to reduced image quality, both in terms of resolution and contrast. Recently, numerous beamforming techniques have been proposed to compensate for this effect, but comparing the different methods is difficult due
Liebgott, Herve   +5 more
openaire   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Frame rate improvement in coherent plane-wave compounding using null subtraction imaging

open access: yesAIP Advances
Coherent plane-wave compounding (CPWC) has attracted significant attention in preclinical research and clinical diagnosis. However, a trade-off exists in CPWC between the image quality and frame rate.
Yijun Xu   +4 more
doaj   +1 more source

High-speed, high-frequency ultrasound, \u3ci\u3ein utero\u3c/i\u3e vector-flow imaging of mouse embryos [PDF]

open access: yes, 2019
Real-time imaging of the embryonic murine cardiovascular system is challenging due to the small size of the mouse embryo and rapid heart rate. High-frequency, linear-array ultrasound systems designed for small-animal imaging provide high-frame-rate and ...
Aristizabal, Orlando   +6 more
core   +1 more source

One-way coherent imaging through a distorting medium using four-wave mixing [PDF]

open access: yes, 1982
A proposal and an analysis are presented for imaging through a distorting medium using field multiplication by four-wave ...
Koch, Thomas L., Yariv, Amnon
core   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Non-destructive testing of composite plates by holographic vibrometry [PDF]

open access: yes, 2014
We report on a wide-field optical monitoring method for revealing local delaminations in sandwich-type composite plates at video-rate by holographic vibrometry.
Atlan, Michael   +5 more
core   +5 more sources

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

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