Results 61 to 70 of about 1,120 (242)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Life at the end of worlds : modelling the biosignatures of microbial life in diverse environments at the end of the habitable lifetimes of Earth-like planets

, 2014
This thesis investigates how increased global mean temperatures on Earth, induced by the increase in the luminosity of the Sun as it ages, change the types of habitable environments on the planet at local scales over the next 3 Gyr.
O'Malley-James, Jack T.
core  

Origin and formation of the regular satellites around planets

Etudes des conditions de formation des satellites glacés de Jupiter dans le cadre de la mission JUICE Les travaux réalisés au cours de cette thèse s'intéressent à l'origine et à la formation des satellites naturels réguliers de Mars et Jupiter qui sont les cibles de futures missions d'exploration spatiale dédiées à leur caractérisation.
openaire   +2 more sources

Low‐Profile, High‐Gain GRIN RF Lenses via Multi‐Material Vat Photopolymerization

Advanced Functional Materials, EarlyView.
We investigate the opportunity of leveraging multi‐material vat photopolymerization printing to manufacture intricate lenses exhibiting permittivity gradients that can increase signal gain in transmitted radiofrequency signals in the X‐ and Ku‐bands. Lenses produced with more distinct low‐loss materials (up to 5) can deliver an 18 dB signal gain with a
Lawrence Romangsuriat, Alexander Peraire‐Bueno, A. John Hart, Randall M. Erb   +3 more
wiley   +1 more source

Replacement and late formation of atmospheric N2 on undifferentiated Titan by impacts

, 2011
Saturn’s moon, Titan, has remarkable surface features—a massive N2 atmosphere and hydrological cycle of CH4—that are often compared with that of Earth^1^. However, the origin and evolution of Titan’s atmosphere remains largely
Toshihiko Kadono, Yasuhito Sekine, Seiji Sugita, Hidenori Genda, Takafumi Matsui   +4 more
core  

Resonant Rotation States of the Jovian and Saturnian Satellites [PDF]

, 2019
Many of the moons of the giant planets are trapped in a 1:1 spin-orbit resonance. Up to now this special rotation state is confirmed by observations for 8 satellites of Jupiter, 15 satellites of Saturn, 15 satellites of Uranus, and 7 satellites of ...
Steinbrügge, G., Stark, Alexander, Roatsch, Thomas, Oberst, Jürgen, Hussmann, Hauke   +4 more
core  

The Outer Planets and their Moons: Comparative Studies of the Outer Planets prior to the Exploration of the Saturn System by Cassini-Huygens

, 2005
This volume gives an integrated summary of the science related to the four giant planets in our solar system. It is the result of an ISSI workshop on «A comparative study of the outer planets before the exploration of Saturn by Cassini-Huygens» which was
Sotin, C, Kallenbach, R, Owen, T. C, Encrenaz, T   +3 more
core   +1 more source

Coupling Anodic Activity and Stability at Ni‐Based Non‐Oxide Catalysts via Coordinating Alcohol Oxidation and Oxygen Evolution

Advanced Functional Materials, EarlyView.
A cooperative and competitive interrelationship between alcohol oxidation (AOR) and water oxidation (OER) was observed on a typical anode catalyst of Ni2P. In situ Raman spectroscopy and electrochemical analyses revealed a specific complementary mechanism between them, in which OER and AOR critically contribute to the activity and stability of anodic ...
Yong Yan, Xinyu Liu, Yuguo Zhao, Hanwen Jian, Huan Zhou, Riyi Zhang, Dong Wang, Peter Schaaf, Lihua Wang, Guangsheng Guo, Xiayan Wang   +10 more
wiley   +1 more source

2D Co‐Mo‐Hydroxide‐Based Multifunctional Material for the Development of H2‐Based Clean Energy Technologies

Advanced Materials, EarlyView.
2D α‐Co(OH)2 interleaved with Mo species displays an appealing dual functionality for the production and use of green hydrogen.Mo incorporation greatly benefits the electrochemical behaviour in Oxygen Evolution Reaction for H2 production, while the magnetocaloric response at liquid H2 temperature paves the way for alternative cryogenic refrigerants ...
Daniel Muñoz‐Gil, Celia Castillo‐Blas, Dawid Krystian Feler, Isabel Gómez‐Recio, Miguel Tinoco, Ana Querejeta‐Fernández, Rodrigo González‐Prieto, Felipe Gándara, Romualdo Santos Silva Jr, Pilar Ferrer, Carlos Prieto, Luc Lajaunie, José Luis Martinez‐Peña, María Luisa Ruiz‐González, José María González‐Calbet   +14 more
wiley   +1 more source

Leaftronics: Bio‐Fractal Scaffolds From Leaf Venation for Low‐Waste Electronics

Advanced Materials, EarlyView.
“Leaftronics” transforms naturally evolved leaf venation into quasi‐fractal scaffolds for sustainable electronics. Polymer‐infiltrated leaf skeletons can be used to fabricate ultra‐smooth, reflow‐ and thin‐film‐compatible decomposable substrates, while making the same lignocellulose networks conducting results in flexible transparent electrodes.
Rakesh Rajendran Nair, Hrisheekesh Thachoth Chandran, Karl Leo, Hans Kleemann   +3 more
wiley   +1 more source