Results 41 to 50 of about 472,109 (307)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Perceptual adjustment to time-compressed Speech: a cross-linguistic study [PDF]

open access: yes, 1998
revious research has shown that, when hearers listen to artificially speeded speech, their performance improves over the course of 10-15 sentences, as if their perceptual system was "adapting" to these fast rates of speech.
Christophe, Anne   +4 more
core   +4 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The African Languages Research Institute: A Milestone in the Development of the Zimbabwean Languages

open access: yesLexikos, 2011
<p>Abstract: This article is an assessment of the work the African Languages Research Institute (ALRI) has done towards developing the indigenous languages of Zimbabwe.
Emmanuel Chabata
doaj   +1 more source

PyFlies: A Domain-Specific Language for Designing Experiments in Psychology

open access: yesApplied Sciences, 2021
The majority of studies in psychology are nowadays performed using computers. In the past, access to good quality software was limited, but in the last two decades things have changed and today we have an array of good and easily accessible open-source ...
Igor Dejanović   +3 more
doaj   +1 more source

Joseph Chamberlain Sixth Form College: report from the Inspectorate (FEFC inspection report; 23/95 and 12/99) [PDF]

open access: yes, 1999
Comprises two Further Education Funding Council (FEFC) inspection reports for the periods 1994-95 and 1998 ...

core  

Progression and assessment in foreign languages at Key Stage 2 [PDF]

open access: yes, 2009
The teaching of primary languages has been increasing steadily, in response to the future entitlement for all Key Stage 2 (KS2) pupils aged 7-11 to learn a foreign language by 2010.
Barnes A.   +7 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Inspection report: Itchen College [PDF]

open access: yes, 2004
Dates of inspection: 1–5 March ...
Barlow, Bev
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

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