Results 51 to 60 of about 2,323,816 (303)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Farmers’ Willingness to Adopt Maize-Soybean Rotation Based on the Extended Theory of Planned Behavior: Evidence from Northeast China

Agriculture
Context: For decades, maize monoculture practices dominated Northeast China, causing significant damage to the local soil and ecological environment.
Yunzheng Zhang, Zainab Oyetunde-Usman, Simon Willcock, Minglong Zhang, Ning Jiang, Luran Zhang, Li Zhang, Yu Su, Zongyi Huo, Cailong Xu, Yuquan Chen, Qingfeng Meng, Xiangping Jia   +12 more
doaj   +1 more source

Evaluation of the impact of the Healthy Start/Départ Santé intervention on improving menu planning practices and improving the congruence between planned menus and actual food served in Saskatchewan childcare centres

Preventive Medicine Reports, 2021
The objective of this study was to evaluate the impact of the Healthy Start/Départ Santé (HS/DS) intervention program on improving menu planning practices and improving the congruence between planned menus and actual food served in licensed childcare ...
Lila Abobakar, Rachel Engler-Stringer, Anne Leis, Hassan Vatanparast   +3 more
doaj   +1 more source

Giving TESOL change a chance: supporting key players in the curriculum change process [PDF]

, 2003
The language of ‘western’ planned and managed TESOL curriculum change aid projects of the 1980–1990s continues to have a strong influence on the terms in which the objectives of 21st century, nationally planned TESOL curriculum change projects are ...
Wedell, M.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Latent Errors and Visible Earned Value: How the Evolutionary Model Integrates Earned Value Metrics with Project System Dynamics

Systems, 2021
A project model is presented that weaves together ideas from earned value project management and systems dynamics. It is able to adjust to increasingly unhealthy actual project behaviors in ways that preserve the signature pattern of the staffing ...
John M. Nevison, Karim J. Chichakly
doaj   +1 more source

Preparing young people with complex needs and their families for transition to adult services [PDF]

, 2019
© RCN Publishing Company Limited 2018Improving survival rates for children and young people with complex health needs requires a robust system for transition to adult services. Effective planning is essential to ensure a smooth transition process that is
Department for Children, Schools and Families, Department of Health, Department of Health, National Institute for Health and Care Excellence   +3 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Analysis Of Project Time Control for the Batulicin Port Road Using the Earned Value Concept Method

The Spirit of Society Journal: International Journal of Society Development and Engagement
Pelaksanan Proyek Jalan Pelabuhan Batulicin merupakan proyek yang penting karena jalan akses The implementation of the Batulicin Port Road Project is an important project because the current access road to Batulicin Port is inadequate.
Muhammad Taufik Novianto, Budi Witjaksana, Hanie Teki Tjendani   +2 more
doaj   +1 more source

When retailing and Las Vegas meet: probabilistic free price promotions [PDF]

, 2016
A number of retailers offer gambling- or lottery-type price promotions with a chance to receive one’s entire purchase for free. Although these retailers seem to share the intuition that probabilistic free price promotions are attractive to consumers, it ...
Ariely, Dan, Mazar, Nina, Shampanier, Kristina   +2 more
core   +2 more sources