Results 71 to 80 of about 2,323,816 (303)
MedEdPORTAL, 2014 Introduction Medical educators have recently been charged with teaching clinicians about healthcare costs and value. The ACGME currently requires under their systems-based practice competency that resident physicians maintain cost awareness while ...
Christopher Moriates +5 more
doaj +1 more source
Exploring the value of a design for service approach to develop public services in the Community Voluntary Sector: a comparative analysis [PDF]
, 2014 This paper presents the findings from two action research case studies that explore the value of using a ‘design for service’ approach to develop public services in the community voluntary sector (CVS).
Lievesley, Matthew +2 more
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Value Creation in Category Management Relationships: A Comparative Analysis [PDF]
, 2017 Category management is a collaborative approach between food manufacturers and retailers to manage product categories rather than individual brands.
Benson, Michael
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Comparison of Drinking Patterns Types against Hydration Status in Young Men and Women
Juara, 2019 Hydration status is important to maintain so that the body does not experience a lack of fluids which is referred to as dehydration and excess fluid called overhydration.
Grisna Febiyanti, Kunjung Ashadi
doaj +1 more source
Cosmology and the neutrino mass ordering
, 2016 We propose a simple method to quantify a possible exclusion of the inverted neutrino mass ordering from cosmological bounds on the sum of the neutrino masses. The method is based on Bayesian inference and allows for a calculation of the posterior odds of
Hannestad, Steen, Schwetz, Thomas
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Study of gain variation as a function of physical parameters of GEM foil
, 2015 The ALICE experiment at LHC has planned to upgrade the TPC by replacing the MWPC with GEM based detecting elements to restrict the IBF to a tolerable value.
Das, Supriya
core +1 more source