Results 81 to 90 of about 161,839 (313)

Leveraging two novel droplet−based single−cell RNA Sequencing platforms: a comparative study with 10x genomics

BMC Genomics
Background Currently, single cell transcriptome profiling technology is gaining popularity, with an increasing number of novel platforms emerging. The development of new technologies is aimed at improving data quality, scale, cost, or labor intensity ...
A. V. Maluchenko, E. S. Avsievich, Ia. S. Zvorygina, Z. G. Antysheva, D. O. Maksimov, M. V. Boytsova, D. V. Tabakov, N. A. Bodunova, O. V. Glazova, D. I. Tychinin, A. V. Bolbat, E. S. Petriaikina, D. V. Svetlichnyy, S. M. Yudin, A. A. Keskinov, V. S. Yudin, M. V. Woroncow, V. I. Skvortsova, J. A. Krupinova, P. Yu Volchkov   +19 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Benchmark of the Oxford Nanopore, EM-seq, and HumanMethylationEPIC BeadChip for the detection of the 5mC sites in cancer and normal samples

Frontiers in Epigenetics and Epigenomics
Introduction: Whole-genome DNA methylation identification is crucial for profiling physiologically and clinically relevant epigenetic changes. Although there are multiple experimental methods, their accuracy, advantages, and disadvantages need to be ...
Kseniia A. Deinichenko, Valentina G. Vynogradskaya, Pavel A. Grebnev, Valeriya M. Mikova, Dmitriy O. Bobylev, Abusaid M. Shaymardanov, Alexey A. Ivashechkin, Marina V. Erokhina, Alexandra I. Akinshina, Anna V. Semyanihina, Anna V. Semyanihina, Sergey I. Mitrofanov, Konstantin S. Grammatikati, Vladimir S. Yudin, Sergey M. Yudin, Antonida V. Makhotenko, Anton A. Keskinov, Sergey A. Kraevoy, Anna S. Makarova, Ekaterina A. Snigir, Dmitry V. Svetlichnyy, Veronika I. Skvortsova   +21 more
doaj   +1 more source

Modest Sociality: Continuities and Discontinuities

Journal of Social Ontology, 2015
A central claim in Michael Bratman’s account of shared agency is that there need be no radical conceptual, metaphysical or normative discontinuity between robust forms of small-scale shared intentional agency, i.e., modest sociality, and individual ...
Pacherie Elisabeth
doaj   +1 more source

The Effect Of Leadership Style, Work Facilities, Use Of Information Technology, And Benefits On Employee Work Motivation In Regional Development Planning Agency Nature Fence City

, 2023
Fherla Yudhi Aguslan, Hardiyansyah Hardiyansyah, Nisma Aprini   +2 more
openalex   +2 more sources

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

The Role of Interpersonal Skills of Village-Owned Enterprise (BUM Desa) Managers in East Sumba Regency Facing the Challenges of Changing Economic Structures

Jurnal Bina Praja
In the current era of information technology and digitalization, the transformation of structural changes in the economy seems to be running so fast that it exceeds the readiness factor of the community itself.
Fransiskus Xaverius Candra Gunawan, Husnah Rahman, Andi Tenri Awaru   +2 more
doaj   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang, Shaoxin Tao, Qiujia Wang, Xiaoyu Xu, Hui Yao, Zheng Liu, Dawei Li, Zhandong Qiu, Jinming Han, Jiangwei Xia, Qi Wang, Jun Sun, Kai Shao, Jiao Li, Shishuang Ruan, Yi Zhong, Jun Guo, Shougang Guo, Yue Huang, Guoliang Chai, Tao Jin, Hongyu Zhou, Junwei Hao, Yinan Zhao   +23 more
wiley   +1 more source

The Influence And Women'sempowerment Agency, Kaur Of Motivation And Leadership Style Onemployee Perform Ance In Family Planning District

, 2023
Fachri Frasetya Fahlevi, Sulisti Afriani, Iswidana Utama Putra   +2 more
openalex   +2 more sources