Results 61 to 70 of about 161,839 (313)

An overview of evaluating the efficacy of microbial pathogens for biological control of the red palm weevil Rhynchophorus ferrugineus (Olivier, 1790) (Coleoptera: Curculionidae) insights from laboratory and field studies

open access: yesEgyptian Journal of Biological Pest Control
Background This overview explores the use of entomopathogenic nematodes (EPNs), fungi (EPFs), bacteria (EPBs), and viruses (EPVs) as biological control strategies against the red palm weevil (RPW) (Rhynchophorus ferrugineus), a significant pest of date ...
Koko Dwi Sutanto   +7 more
doaj   +1 more source

ANALYSIS OF RISK FACTORS AND THE IMPACT OF BULLYING BEHAVIOR ON ADOLESCENTS IN JUNIOR HIGH SCHOOLS IN GRESIK REGENCY

open access: yesJurnal Ilmiah Kesehatan
Bullying is a serious problem, as it can have a long-term impact on severe psychological problems, such as low self-esteem to deep depression, aggression, and school refusal which can lead to dropping out of school.
suyanto   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

On The Bureaucrats'Behavior in Public Planning Agency

open access: yesINFRASTRUCTURE PLANNING REVIEW, 1998
Existing studies on the bureaucracy have not dealt with organization structure or transmission of information clearly. In this paper we build a model for the Bureaucrats' Behavior on the basisof game theory. We focus on Herd Behavior of bureaucrats which depends on the probability of their ability or transmission of information change, bureaucrats ...
OKADA, Masami   +2 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Antioxidant and α-glucosidace inhibitory activities of the Andrographis paniculata Nees. ultrasonic leaf extract

open access: yesPakistan Journal of Pharmaceutical Sciences
Different natural products derived from plants have long been utilized as traditional herbal remedies to treat a variety of ailments, and these substances have inspired the design, discovery, and development of new pharmaceuticals.
Andita Utami   +9 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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