Results 231 to 240 of about 1,625,954 (310)

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

First clinical implementation of dynamic tumor-tracking volumetric modulated arc therapy with a gimbal-mounted linac: short delivery time and high precision. [PDF]

J Radiat Res
Kishi N, Nakamura M, Hirashima H, Adachi T, Yoneyama M, Kawata K, Kishigami Y, Ogata T, Murakami T, Iizuka Y, Seno H, Mizowaki T.   +11 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Negotiating assistive technologies and AI in inclusive education: professional agency in neurodivergent contexts. [PDF]

Front Child Adolesc Psychiatry
Marras A, Pasqualotto A.
europepmc   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Partnership Between Local Health Departments and Schools of Public Health or Public Health Programs: An Analysis of National Profiles of Local Health Departments. [PDF]

Healthcare (Basel)
Shah GH, Massengale K, Nguyen TH.
europepmc   +1 more source

Emergence of Tigecycline-Resistant Pseudomonas aeruginosa Harbouring tmexC6D6-toprJ1b From Hospital Sewage in Japan. [PDF]

Environ Microbiol Rep
Maehana S, Suzuki M, Ishimura N, Izawa H, Eda R, Nakamura M, Amarasiri M, Furukawa T, Kojima F, Sei K, Kubo M.   +10 more
europepmc   +1 more source

Clarity and consistency in government-funded implementation strategies associated with greater evidence-based practice reach: a mixed-method comparative case study. [PDF]

Implement Sci
Lee M, Hunter SB, Tumendemberel B, Shiferaw M, Godley MD, Purtle J, Aarons GA, Dopp AR.   +7 more
europepmc   +1 more source

Mapping the Use of Real-World Evidence Across the EU Health Technology Assessment Regulation: Methodological Considerations, Challenges, and Opportunities for Harmonization. [PDF]

J Mark Access Health Policy
Sarri G, Liljas B, Abrams KR, Duffield SJ, Bharmal M.   +4 more
europepmc   +1 more source

From cultural constraints to structural resilience: a comparative analysis of end-of-life care policies in China, South Korea, the U.S., and the U.K. [PDF]

Front Public Health
Luo S, Cho D, Cho J.
europepmc   +1 more source