Results 101 to 110 of about 4,410,940 (319)
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
Crisis management and planning
Nação e Defesa, 2011 O autor analisa o processo de gestão de crises e planeamento da União Europeia em termos daquilo que foi e deverá ser ainda feito. O treino é sublinhado como um ponto‑chave para o desenvolvimento das capacidades civis e não só. A União Europeia, como um todo, tem de fazer muito mais para aperfeiçoar o seu papel como actor global.
openaire +2 more sources
Karst, GIS and geological hazard planning and management in Great Britain [PDF]
, 2010 The British Geological Survey (BGS) database of karst features for the United Kingdom include dolines, cave entrances, stream sinks, resurgences and building damage; data for approximately half of the country has so far been gathered.
Cooper, A.H., Farrant, A.R., Price, S.J.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Environmental planning and management [PDF]
Environmental Science and Pollution Research, 2019 Hamid Reza Jafari +2 more
openaire +2 more sources
Urban Ecosystem Services for Resilience Planning and Management in New York City
Ambio, 2014 We review the current state of knowledge about urban ecosystem services in New York City (NYC) and how these services are regulated, planned for, and managed.
T. McPhearson +2 more
semanticscholar +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Dynamic Optimization of Exclusive Bus Lane Location Considering Reliability: A Case Study of Beijing
Applied SciencesFor metropolises like Beijing, heavy congestions cause transit passengers’ unreliable travel time, including in vehicle time and waiting time. Comparing with other managerial measures, designing a lane for bus use only is an effective method to improve ...
Weibin Kou +3 more
doaj +1 more source
A primary investigation of strategic management in further education (FE) in the small island state of Malta : quo vadis? [PDF]
, 2015 This paper investigates the presence of a strategic management regime in the further education (FE) sector in Malta using data gathered in 2012. In this way the type of strategic systems followed (if present) and their implementation is delineated. A
Zarb, Nicholas
core
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source