Results 61 to 70 of about 22,802 (294)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Efficient and effective solution procedures for order acceptance and capacity planning. [PDF]
This paper investigates dynamic order acceptance and capacity planning under limited regular and non-regular resources. Our goal is to maximize the profits of the accepted projects within a finite planning horizon.
Herbots, Jada +2 more
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Programming Procedures for Farm and Home Planning under Variable Price, Yield and Capital Quantities, November 1960 [PDF]
, 1960 This study was initiated to develop and improve linear programming models which might have greater application to the planning of individual farm businesses.
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Evaluation of Eight Project Selection Methods: the Case of Information Systems
Estudios de Administración, 1997 Determining the priorities of projects is an essential step in the planning process. Usually, the limited availability of resources prohibits the simultaneous execution of all proposed projects, A number of project selection methods have been developed ...
Eelko K.R.E Huizingh, Hans C.J. Vrolijk
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Planning a cultural community festival : the power of politics
, 2001 Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 2001.Includes bibliographical references (p. 117-119).This investigation is catalyzed by my interest in the impact that cultural planning has had on the physical
Lasso, Ana Maria, 1976-
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, 2019 Time planning of software projects is a complex process for almost all companies. Uncertainties about effort required may cause underestimation or overestimation.
Basar, Ayfer
core +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Ten-T large projects - investments and costs
, 2022 The literature reports on substantial planning and procurement failures of large transport infrastructure projects. This study should elaborate if and how TEN-T co-funded projects are affected by such operational problems and should provide ...
Schade, Wolfgang +4 more
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source