Results 61 to 70 of about 344,496 (285)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Proposal of a machining features recognition method for 5-axis index milling on multi-tasking machine tools

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2020
Multi-tasking machine tools that can deal with several kinds of machining methods including turning and 5-axis control milling are attracted to achieve highly efficient machining in recent years.
Yuto WATANABE, Keiichi NAKAMOTO
doaj   +1 more source

How the consumer confidence index could increase air travel demand forecast accuracy? [PDF]

open access: yes, 2012
Because of the complex nature of the air transportation industry with continuous changes in the environment, the past records of air traffic forecasters, either using trend extrapolation or causal models or even more sophisticated methods have not ...
Teyssier, Narjesse
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Energy sector planning using multiple-index pinch analysis

open access: yes, 2017
Pinch analysis was initially developed as a methodology for optimizing energy efficiency in process plants. Applications of pinch analysis applications are based on common principles of using stream quantity and quality to determine optimal system ...
Tan, Raymond Girard R.   +11 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Developing a Speed-Based Congestion Severity Index Using the Clustering Technique for Developing Countries

open access: yesCommunications
A novel approach for traffic congestion assessment has been presented using percentile speeds as key indicators, focusing on urban roads. By evaluating the 98th, 85th, and 15th percentile speeds, authors of the research developed a congestion severity ...
Malaya Mohanty   +2 more
doaj   +1 more source

Gahai agropolitan project in eradicating poverty: multidimensional poverty index

open access: yes, 2018
The planning and development of Agropolitan Project in Malaysia began in 2007 and was aimed at eradicating extreme poverty in Malaysia. This study aims to discuss the design and construction of Agropolitan Project in eradicating extreme poverty among its
Part Time Nik Zainun binti Nik Mood
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Planning to be productive: the detailed retirement planning strategies of Australian pre-retirees [PDF]

open access: yes, 2012
Australia’s ageing population has resulted in a large cohort of Australians approaching retirement. Policy responses have recognised the significance of this, seeking to strengthen the labour force participation of older Australians to, in part, meet

core  

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