Results 91 to 100 of about 6,656,703 (306)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Soil nutrient availability affects tundra plant community composition and plant–vole interactions
Climate change in the Arctic is predicted to drastically alter carbon and nutrient pools, plant communities, and plant–animal interactions. We examined how four levels of long-term (16 years) nutrient addition in moist acidic tundra affected plant ...
Nicole Williamson +2 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Induced disease resistance [PDF]
During the co-evolutionary arms race between plants and pathogens, plants evolved a sophisticated defense system to ward off their enemies. In this plant immune system, plant receptor proteins recognize non-self molecules of microbial origin, which leads
van Wees, Saskia +4 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbial control of root-pathogenic fungi and oomycetes [PDF]
The rhizosphere is a complex and dynamic environment in which microbes introduced to control root pathogens must establish and maintain populations of sufficient size and activity to antagonize pathogens directly or by manipulating the host plant’s own ...
Bakker, P.A.H.M. +5 more
core +1 more source
Earthworm effects on native grassland root system dynamics under natural and increased rainfall
Earthworms (EWs) can modify soil structure and nutrient availability, and hence alter conditions for plant growth through their burrowing and casting activities.
John A. Arnone +3 more
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Emerging roles of tetraspanins in plant inter-cellular and inter-kingdom communication
Inter-cellular and inter-kingdom signaling systems of various levels of complexity regulate pathogenic and mutualistic interactions between bacteria, parasites, and fungi and animal and plant hosts. Inter-kingdom interactions between mutualistic bacteria
Saul Jimenez-Jimenez +5 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

