Results 241 to 250 of about 353,600 (336)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Plant community, ecosystem, and abiotic data from a global change experiment in mountain grasslands in Norway. [PDF]
Halbritter AH +11 more
europepmc +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Predicting sugar beet leaf area index: evaluating performance of double sigmoid functions under different irrigation and plant density scenarios. [PDF]
Shirazi SHM +4 more
europepmc +1 more source
Financial and economic aspects of organic medicinal plant growing in Ukraine
Nikitiuk Yu., Sologub Yu.
openalex +1 more source
TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Organic amendments to potato soils inconsistently enrich yield-associated soil microbiota across growing regions of the continental US. [PDF]
Klasek SA +5 more
europepmc +1 more source

