Results 251 to 260 of about 353,600 (336)
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Plant Root Architectural Traits Mediate a Trade-Off Between Suppression and Tolerance of Competitors. [PDF]
Salinas H +3 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Changes in Growth and Chemical Composition of the Essential Oil from Flowers and Leafy Stems of <i>Lavandula angustifolia</i> Grown in Media Amended with Bark and Sewage Sludge. [PDF]
Zawadzińska A +4 more
europepmc +1 more source
METAL NANOPARTICLES – THEIR USE AND IMPACT ON PLANTS GROWING IN LABORATORY CONDITIONS
Martyna BEDNAREK +2 more
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Model of leaf biomass partitioning coefficient in different main stem leaf ranks of rapeseed (Brassica napus L.). [PDF]
Zhang W +7 more
europepmc +1 more source

