Results 161 to 170 of about 7,630,762 (341)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
The flora of the Cayuga Lake Basin, New York. Vascular plants
, 1926 K M Wiegand, Arthur J. Eames
openalex +2 more sources
A sample plant design for System 6 [PDF]
, 1984 Hugh W. Reynolds, Bruce G. Hansen
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Ion Transport in Plant Cell Shrinkage During Death
Frontiers in Cell and Developmental Biology, 2020 François Bouteau +3 more
doaj +1 more source
Ethnobotanical survey on plants in Pashang village, Gonabad (Khorasan Razavi, Iran) [PDF]
Journal of Medicinal PlantsBackground: Documentation, preservation, and revival of information on how to use the medicinal plants, are among the leading research priorities in Khorasan with its long history. Objectives: This research aimed to document the wild medicinal plants and
Sholeh Ghollasimod, H. Reza Asa
doaj