Results 121 to 130 of about 146,240 (299)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Light-related variation in sapling architecture of three shade-tolerant tree species of the Mexican rain forest

, 2008
The crown architecture of three shade-tolerant tree species (two subcanopy and one mid-canopy) was analyzed in relation to the light regime of the forest understorey.
Bongers, F, Meave, J., Bongers, F., Martinez-Sanchez, J.L., Martínez-Sánchez, JL, Meave del Castillo, Jorge Arturo   +5 more
core   +1 more source

Pseudomonas PS01 Isolated from Maize Rhizosphere Alters Root System Architecture and Promotes Plant Growth

, 2020
The objectives of this study were to evaluate the plant growth promoting effects on Arabidopsis by Pseudomonas sp. strains associated with rhizosphere of crop plants grown in Mekong Delta, Vietnam.
Minh Thi Thanh Hoang, Thanh Nguyen Chu, Le Van Bui   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Timing effect of high temperature exposure on the plasticity of internode and plant architecture in maize

Journal of Integrative Agriculture
The occurrence of high temperature (HT) in crop production is becoming more frequent and unpredictable with global warming, severely threatening food security.
Binbin Li, Xianmin Chen, Tao Deng, Xue Zhao, Fang Li, Bingchao Zhang, Xin Wang, Si Shen, Shunli Zhou   +8 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Genetic architecture of plant stress resistance: multi-trait genome-wide association mapping [PDF]

, 2017
Plants are exposed to combinations of various biotic and abiotic stresses, but stress responses are usually investigated for single stresses only. Here, we investigated the genetic architecture underlying plant responses to 11 single stresses and several
Huang, P., Davila Olivas, N.H., Coolen, Silvia, Smant, G., van Eeuwijk, F.A., van Wees, S.C.M., Julkowska, M.M., Testerink, C., Jongsma, M.A., Coolen, S., Usadel, B., Kloth, K.J., Cheng, X., Warmerdam, S., Julkowska, Magdalena M., Vosman, B., Pieterse, C.M.J., Bouwmeester, H.J., Bac-Molenaar, J.A., Ruyter-Spira, C., Dijk-Fradin, E.F., van, Broekgaarden, C., Thoen, H.P.M., Schaik, C.C., van, Molenaar, J.A., Heerwaarden, J., van, van Heerwaarden, J., Keurentjes, J.J.B., Eeuwijk, F.A., van, Visser, R.G.F., Aarts, M.G.M., van Pelt, J.A., Bouwmeester, H.J.; id_orcid, Ligterink, W., Ruyter-Spira, C.P., Kruijer, W., Thoen, M.P.M., van Schaik, C.C., Bucher, J., Vreugdenhil, D., Dicke, M., Fradin, E.F., Voorrips, R., Busscher-Lange, J., van Wees, Saskia C.M., van Dijk-Fradin, E.F., Voorrips, R.E., Wees, Saskia C.M., van, Bakker, J., Kruijer, W.T., Huang, P.-P., van Loon, J.J.A., Pieterse, Corné M.J., Wiegers, G.L.   +53 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A Novel Mutation of the NARROW LEAF 1 Gene Adversely Affects Plant Architecture in Rice (Oryza sativa L.)

, 2020
Plant architecture is critical for enhancing the adaptability and productivity of crop plants. Mutants with an altered plant architecture allow researchers to elucidate the genetic network and the underlying mechanisms.
Subudhi, Prasanta K, Subudhi, Prasanta K., Coronejo, Sapphire, Garcia, Richard S., Richard S. Garcia, Garcia, Richard S, Teresa B. De Leon, Sapphire Coronejo, De Leon, Teresa B., Prasanta K. Subudhi, De Leon, Teresa B   +10 more
core   +1 more source

Editorial: Plant architecture: structure, development, evolution, and molecular/genetic regulation

Frontiers in Plant Science, 2023
Abelardo Carlos Vegetti
doaj   +1 more source