Results 141 to 150 of about 169,947 (260)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Solvent-Dependent GC-MS Fingerprinting of Lipophilic Constituents in <i>Syzygium polyanthum</i> Leaves: A Baseline Study for Future Greener Extraction Optimization. [PDF]

Molecules
Paat FJ, Sintaro S.
europepmc   +1 more source

Mapping plant area index of tropical forest by Lidar: calibrating ALS with TLS

, 2015
Highlights: - We compare Plant Area Density (PAD) profiles derived from Terrestrial Laser Scanning (TLS) and contemporaneous Aerial Laser Scanning (ALS) in dense tropical forest- Poor sampling of the lower part of the canopy profile by ALS is mitigated by using a multiple resolution approach- Anisotropy of transmittance revealed by TLS allows further ...
Vincent, Grégoire, Dauzat, Jean, Antin, Cécile, Grau, Eloi, Durrieu, Sylvie   +4 more
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Patterns and Drivers of Spontaneous Plant Diversity in Urban Wastelands Across 17 Cities on the Qinghai-Tibet Plateau. [PDF]

Ecol Evol
He L, Gao Z, Yao Y, Lan L, Yu X, Yang Y, Luo X, Yang R, Wang J, Hu Y, La Q, Da L.   +11 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Exogenous application of bio-regulators and pinching operations on physiological efficacy, phenology, and productivity of bottle gourd (Lagenaria siceraria (Mol.) Standl). [PDF]

BMC Plant Biol
Rehan, Tiwari A, Nair R, Sharma A, Mohammadi M, Sharma S, Das S, Thakur S, Sharma U.   +8 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Woody Plant Diversity and Community Structure Along Elevational and Soil Gradients in <i>Betula platyphylla</i> Forests, Southeastern Tibetan Plateau. [PDF]

Ecol Evol
Norbu N, Wang RF, Dolma D, Tashi S, Jiacuo Y, Zeng ZF, Bonjor N, Tso N, Wang JW, Qiong.   +9 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source