Results 31 to 40 of about 169,947 (260)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Canopy density modifies leaf predisposition to Plasmopara viticola but does not affect downy mildew epidemics in grapevine

Frontiers in Agronomy
Certain agricultural practices may influence the susceptibility of the plant tissue to pathogens, including practices that influence the canopy density, which in turn may favor disease development through changes in the canopy microclimate.
Giorgia Fedele, Giorgia Fedele, Vittorio Rossi, Vittorio Rossi, Margherita Furiosi, Margherita Furiosi, Tito Caffi, Tito Caffi   +7 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Effects of Different Planting Modes on Peanut Photosynthetic Characteristics, Leaf Area Index and Yield in the Sandy Area [PDF]

Proceedings of the 2015 International Conference on Mechatronics, Electronic, Industrial and Control Engineering, 2015
Five planting modes were designed to study photosynthetic characteristics, leaf area index and yield of peanut variety as Fu Hua 17 in order to provide theoretical basis for peanut yield increase in the sandy area. Results showed that the mode of peanuts planted for double rows in the border check with mulched drip irrigation (T1) was the best.
Qingwen Shi, Xiaori Han, Yan Lu, Qiaobo Song, Yifei Liu, Huixin Wang   +5 more
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Growth analysis and yield of traditional, intermediate and modern upland rice cultivars

Pesquisa Agropecuária Tropical, 2012
The growth analysis allows the characterization and understanding of the upland rice cultivars development. This study aimed at characterizing, by using the growth analysis, the physiological components and agronomic performance, as well as the ...
Rita de Cassia Felix Alvarez, Carlos Alexandre Costa Crusciol, Adriano Stephan Nascente   +2 more
doaj   +1 more source

Biodiversity of Plants and Birds in Reclamation Area of PT Bukit Asam, Muara Enim, South Sumatera

Jurnal Manajemen Hutan Tropika, 2016
Mining activities will reduce species diversity, whereas forest reclamation would restore the species diversity, which was previously a forested area.
Dimaz Danang Al-Reza, Lilik Budi Prasetyo, Rahmad Hermawan   +2 more
doaj   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source