Results 141 to 150 of about 6,658,736 (302)
WRINKLED1 as a novel 14-3-3 client : function of 14-3-3 proteins in plant lipid metabolism
, 2018 The conserved plant 14-3-3 proteins (14-3-3s) function by binding to phosphorylated client proteins to regulate their function. Previous studies indicate that 14-3-3s are involved in the regulation of plant primary metabolism; however, not much is known ...
Ma, Wei, Kong, Que
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Wolf Presence Disrupts Seasonal Variation in Hair Cortisol Among Free‐Ranging Beef Cattle
Ecology and EvolutionUnderstanding how predator reintroduction indirectly affects prey physiology remains poorly understood. We examined hair cortisol concentrations in 79 beef cattle from nine herds across California's Sierra Nevada, comparing herds exposed to the Lassen ...
Christina M. Nord +6 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Community-managed forests can secure forest regrowth and permanence in human-modified landscapes
Global Ecology and ConservationDeforestation can impair ecosystem functions, reduce biodiversity, and accelerate climate change. One strategy proposed to decrease deforestation and promote recovery of degraded areas involves community management of forests: entrusting local ...
Elihuruma Wilson Kimaro +4 more
doaj +1 more source
, 2015 Plants are under the constant threat of microbial pathogens. To defend themselves, plants have developed immune responses (including for example synthesis of antimicrobial secondary metabolites, production of PR proteins or reinforcement of cell wall ...
Fournier, Carine +4 more
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source