Results 191 to 200 of about 546,038 (302)

How to eat an idea-A roadmap for translation and impact in plant biology. [PDF]

Plant Physiol
Napier JA.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Exploring the untapped potential of single-cell and spatial omics in plant biology. [PDF]

New Phytol
Nobori T.
europepmc   +1 more source

Data Management and Modeling in Plant Biology. [PDF]

Front Plant Sci, 2021
Krantz M, Zimmer D, Adler SO, Kitashova A, Klipp E, Mühlhaus T, Nägele T.   +6 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Manipulation of targeted protein degradation in plant biology. [PDF]

Biochem Soc Trans
Rojas-Pierce M, Bednarek SY.
europepmc   +1 more source

Pisum sativum has no competitive responses to neighbors: A case study in (non)reproducible plant biology. [PDF]

Plant Direct, 2022
Mobley ML, Kruse AS, McNickle GG.
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Editorial: Plant biology for indoor vertical farming: a multi-discipline approach to controlled environment agriculture. [PDF]

Front Plant Sci
Gauthier PPG, Marcelis LFM.
europepmc   +1 more source

From Classical to Modern Computational Approaches to Identify Key Genetic Regulatory Components in Plant Biology. [PDF]

Int J Mol Sci, 2023
Acién JM, Cañizares E, Candela H, González-Guzmán M, Arbona V.   +4 more
europepmc   +1 more source