Results 51 to 60 of about 255,131 (242)
Application of Plant Viruses in Biotechnology, Medicine, and Human Health
Viruses, 2021 Plant-based nanotechnology programs using virus-like particles (VLPs) and virus nanoparticles (VNPs) are emerging platforms that are increasingly used for a variety of applications in biotechnology and medicine.
Srividhya Venkataraman +1 more
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Biotechnology and Plant Breeding
Biotechnology & Biotechnological Equipment, 1993 ABSTRACTPlant breeding is an integrative discipline that is defined by the product, i. e., a crop cultivar. Principles of breeding provide the framework, while technologies (including biotechnology) provide the tools for implementation. The successful execution of plant breeding depends on: availability of genetically variable populations, effective ...
openaire +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Recent advances and novelties in the thin cell layer-based plant biotechnology – a mini-review
BioTechnologia, 2019 Plant thin cell layers (TCLs), which consist of a few layers of cells, are typically 0.5–1 mm thick. After the first application of TCLs to tobacco in 1943, and after 45 years of their practical application to plant tissue culture, TCLs have proven to be
Jaime da Silva, Judit Dobránszki
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Plant Biotechnology: Transgenic Crops
, 2008 Transgenesis is an important adjunct to classical plant breeding, in that it allows the targeted manipulation of specific characters using genes from a range of sources. The current status of crop transformation is reviewed, including methods of gene transfer, the selection of transformed plants and control of transgene expression.
Shewry, P. R. +2 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Plant Genetic Improvement by Biotechnology
Biotecnología Vegetal, 2006 Plant Genetic Improvement by ...
Instituto Biología de las Plantas
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source