Results 61 to 70 of about 644,214 (270)
Biotechnology and Plant Breeding
Biotechnology & Biotechnological Equipment, 1993 ABSTRACTPlant breeding is an integrative discipline that is defined by the product, i. e., a crop cultivar. Principles of breeding provide the framework, while technologies (including biotechnology) provide the tools for implementation. The successful execution of plant breeding depends on: availability of genetically variable populations, effective ...
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plant Biotechnology: Applications in In Vitro Plant Conservation and Micropropagation
HorticulturaeMicropropagation and conservation using in vitro methods are one of the most important technologies used to maintain the gene pool and genetic diversity [...]
Rupesh Kumar Singh, Vasiliy A. Chokheli
doaj +1 more source
Advanta: Worldwide challenges [PDF]
, 2001 Includes bibliographical references.Advanta, headquartered in the Netherlands, is the sixth largest seed company in the world. It sells seeds for a broad range of field crops in many different regions.
Bijman, J.
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Aptamers as emerging tools for plant disease management: From biosensing to active modulation
iScienceSummary: Conventional methods for plant disease detection and management often face limitations in sensitivity, specificity, and field applicability. Aptamers, with high affinity and specificity, present a promising alternative.
Fuguo Liu +5 more
doaj +1 more source
Impact of Biotechnology on Plant Breeding [PDF]
The application of modern biotechnology to plant breeding is considered to be more efficient and quicker than conventional breeding techniques in the development of new and more resilient crop varieties. To test the impact that biotechnology is having on
Hock, Cricket +3 more
core +1 more source