Results 171 to 180 of about 599,263 (289)

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Integrating molecular genetics with plant breeding to deliver impact. [PDF]

Plant Physiol
Sharma R, Yang CJ, Rossi N, Irving E, Tuffin A, Aliki H, Powell W, Dawson IK.   +7 more
europepmc   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

In silico prediction of variant effects: promises and limitations for precision plant breeding. [PDF]

Theor Appl Genet
Sendrowski J, Bataillon T, Ramstein GP.
europepmc   +1 more source

Toward plant breeding for multicrop systems. [PDF]

Proc Natl Acad Sci U S A, 2023
Moore VM, Peters T, Schlautman B, Brummer EC.   +3 more
europepmc   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Optimising parent selection in plant breeding: comparing metaheuristic algorithms for genotype building. [PDF]

Theor Appl Genet
Yadav S, Dillon S, McNeil M, Dinglasan E, Mago R, Dodds P, Hickey L, Hayes BJ.   +7 more
europepmc   +1 more source

Toward Transgene-Free Transposon-Mediated Biological Mutagenesis for Plant Breeding. [PDF]

Int J Mol Sci, 2023
Kirov I.
europepmc   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Fast-forwarding plant breeding with deep learning-based genomic prediction. [PDF]

J Integr Plant Biol
Gao S, Yu T, Rasheed A, Wang J, Crossa J, Hearne S, Li H.   +6 more
europepmc   +1 more source