Results 41 to 50 of about 8,546,204 (300)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Background Dissection of complex plant cell wall structures demands a sensitive and quantitative method. FTIR is used regularly as a screening method to identify specific linkages in cell walls.
Shouvik Das +6 more
doaj +1 more source
Pro-pectin methylesterases as zymogens for plant cell wall mediated immunity
Plants modulate the activity of immunity-related pectin methylesterase (IT-PME) against microbes (Del Corpo et al., 2020). This process could induce the formation of "egg box" structures, resulting in stiffening of the cell wall.
Vincenzo Lionetti +2 more
core
Involvement of bacterial TonB-dependent signaling in the generation of an oligogalacturonide damage-associated molecular pattern from plant cell walls exposed to Xanthomonas campestris pv. campestris pectate lyases [PDF]
Vorhölter F-J, Wiggerich H-G, Scheidle H, et al. Involvement of bacterial TonB-dependent signaling in the generation of an oligogalacturonide damage-associated molecular pattern from plant cell walls exposed to Xanthomonas campestris pv.
Vishaldeep Kaur Sidhu +24 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Staining and immunodetection by light microscopy are methods widely used to investigate plant cell walls. The two techniques have been crucial to study the cell wall architecture in planta, its deconstruction by chemicals or cell wall-degrading enzymes ...
Yves Verhertbruggen +8 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
C2H2 zinc finger proteins (C2H2-ZFPs), one of the largest transcription factor families in plants, exhibit unique functional diversity in woody and horticultural species due to their modular architecture and regulatory flexibility.
Minhui Li +8 more
doaj +1 more source
Cell wall integrity signalling and innate immunity in plants
All plant pathogens and parasites have had to develop strategies to overcome cell walls in order to access the host’s cytoplasm. As a mechanically strong, multi-layered composite exoskeleton, the cell wall not only enables plants to grow tall but also ...
Thomas Sebastian Nuhse
doaj +1 more source

