Results 81 to 90 of about 557,103 (299)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Comparative moisture and heat sorption properties of fibre and shiv derived from hemp and flax [PDF]

, 2019
: Unlike many mineral-based insulation materials bio-based lignocellulosic fibre and shiv offer a number of benefits including thermal and hygroscopic properties. The microstructure, porosity and chemical compositions of the plant cell walls play a major
Ansell, Martin, Hussain, Atif, Jiang, Yunhong, Lawrence, Michael, Walker, Pete   +4 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

QTL mapping for yield contributing traits in mungbean (Vigna radiata L.) using a RIL population

Scientific Reports
Mungbean (Vigna radiata L.) is one of the most important yet genomically under-researched leguminous food crop. Its productivity is low due to the complex nature of yield realization, which is regulated by various yield-contributing traits.
Shashidhar B. Reddappa, Muralidhar S. Aski, Gyan P. Mishra, Soma Gupta, Kumbarahally M. Shivaprasad, Subodh K. Sinha, Ranjeet R. Kumar, Anirban Roy, Dwijesh C. Mishra, Shouvik Das, Prashant Anupama Mohan Pawar, Ramakrishnan Madhavan Nair, Harsh K. Dikshit   +12 more
doaj   +1 more source

Defects in leaf epidermis of Arabidopsis thaliana plants with CDKA;1 activity reduced in the shoot apical meristem [PDF]

, 2012
In Arabidopsis thaliana, like in other dicots, the shoot epidermis originates from protodermis, the outermost cell layer of shoot apical meristem. We examined leaf epidermis in transgenic A.
Borowska-Wykret, Dorota, De Veylder, Lieven, Elsner, Joanna, Kwiatkowska, Dorota   +3 more
core   +2 more sources

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Cell wall composition and digestibility alterations in Brachypodium distachyon achieved through reduced expression of the UDP-arabinopyranose mutase

Frontiers in Plant Science, 2015
Nucleotide-activated sugars are essential substrates for plant cell-wall carbohydrate-polymer biosynthesis. The most prevalent grass cell wall sugars are glucose (Glc), xylose (Xyl), and arabinose (Ara).
David M. Rancour, Ronald D. Hatfield, Jane M Marita, Nicholas A. Rohr, Robert J Schmitz   +4 more
doaj   +1 more source

Open field study of some Zea mays hybrids, lipid compounds and fumonisins accumulation [PDF]

, 2015
Lipid molecules are increasingly recognized as signals exchanged by organisms interacting in pathogenic and/or symbiotic ways. Some classes of lipids actively determine the fate of the interactions.
Battilani, Paola, Cirlini, Martin, Dall’Asta, Chiara, Fanelli, Corrado, Galaverna, Gianni, Giorni, Paola, Ludovici, Matteo, Reverberi, Massimo, Scala, Valeria   +8 more
core   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Using antibodies to understand the complexities of plant cell walls [PDF]

, 2017
The rigid structures at the surface of plant cells are some of the most structurally complex & mechanically robust sets of biomaterials in nature. Given the dominance of plants on land, these cell walls are highly abundant and are a major repository of ...
Know, John Paul
core