Results 211 to 220 of about 16,481,877 (361)

A novel cis-element enabled bacterial uptake by plant cells. [PDF]

open access: yesNat Plants
Cathebras C   +8 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

FE-SEM visualization of cortical microtubules in plant cells using freeze-fracture techniques. [PDF]

open access: yesPlant Methods
Hatano T   +6 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Isolation of Whole Esophageal Gland Cells from Plant-Parasitic Nematodes for Transcriptome Analyses and Effector Identification

open access: yes, 2013
Esophageal glands of plant-parasitic nematodes are highly specialized cells whose gene expression products include secreted effector proteins, which govern nematode parasitism of host plants. Therefore, elucidating the transcriptomes of esophageal glands
Peng, Jiqing   +3 more
core  

Fluorescence staining of the nucleus in living plant cells using dimidium bromide. [PDF]

open access: yesPlant Biotechnol (Tokyo)
Ichikawa S, Kitamura M, Kodama Y.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Hypoxia-activated fluorescent probes as markers of oxygen levels in plant cells and tissues. [PDF]

open access: yesNew Phytol
Perri M   +10 more
europepmc   +2 more sources

Single-cell metabolome and RNA-seq multiplexing on single plant cells. [PDF]

open access: yesProc Natl Acad Sci U S A
Kang M   +8 more
europepmc   +1 more source

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