Results 61 to 70 of about 556,291 (294)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Transcriptome analysis of Thevetia peruviana cell suspensions treated with methyl jasmonate reveals genes involved in phenolics, flavonoids and cardiac glycosides biosynthesis

open access: yesFrontiers in Plant Science
Thevetia peruviana (Pers.) K. Schum is a tropical shrub with recognized ethnomedicinal applications associated with the presence of secondary metabolites (SMs), which exhibit cardiotonic, antioxidant, antimicrobial and anticancer activities.
Olmedo Cuaspud   +9 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Sodium transport system in plant cells

open access: yesFrontiers in Plant Science, 2013
Since Sodium, Na, is a non-essential element for the plant growth, the molecular mechanism of Na+ transport system in plants has remained elusive for the last two decades.
Toshio eYamaguchi   +2 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Epigenetic alterations in bioaccumulators of cadmium: Lessons from mammalian kidneys and plants

open access: yesEnvironment International
Faced with unpredictable changes in global weather patterns, release and redistribution of metals through land erosion and water movements add to the increasing use of metals in industrial activities causing high levels of environmental pollution and ...
Stephanie Frings   +2 more
doaj   +1 more source

Plant stress RNA-seq Nexus: a stress-specific transcriptome database in plant cells

open access: yesBMC Genomics, 2018
Background Abiotic and biotic stresses severely affect the growth and reproduction of plants and crops. Determining the critical molecular mechanisms and cellular processes in response to stresses will provide biological insight for addressing both ...
Jian-Rong Li   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Oxidative Protein-Folding Systems in Plant Cells

open access: yesInternational Journal of Cell Biology, 2013
Plants are unique among eukaryotes in having evolved organelles: the protein storage vacuole, protein body, and chloroplast. Disulfide transfer pathways that function in the endoplasmic reticulum (ER) and chloroplasts of plants play critical roles in the
Yayoi Onda
doaj   +1 more source

On the track of transfer cells formation by specialized plant-parasitic nematodes

open access: yesFrontiers in Plant Science, 2014
Transfer cells are ubiquitous plant cells that play an important role in plant development as well as in responses to biotic and abiotic stresses.
Natalia eRodiuc   +4 more
doaj   +1 more source

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