Results 81 to 90 of about 1,543,932 (340)
PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer +21 morewiley +1 more sourceDecrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier +4 morewiley +1 more sourceCharacterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane +9 morewiley +1 more sourceTRY plant trait database - enhanced coverage and open access [PDF]
, 2020 Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits ...Aakala, T, Abedi, M, Acosta, ATR, Adamidis, GC, Adamson, K, Aiba, M, Albert, CH, Alcantara, JM, Alcazar, CC, Aleixo, I, Ali, H, Amiaud, B, Ammer, C, Amoroso, MM, Anand, M, Anderson, C, Anh, TDL, Anten, N, Antos, J, Apgaua, DMG, Ashman, TL, Asmara, DH, Asner, GP, Aspinwall, M, Atkin, O, Aubin, I, Baastrup-Spohr, L, Bahalkeh, K, Bahn, M, Baker, T, Baker, WJ, Bakker, JP, Baldocchi, D, Baltzer, J, Banerjee, A, Baranger, A, Barlow, J, Barneche, DR, Baruch, Z, Bastianelli, D, Battles, J, Bauerle, W, Bauters, M, Bazzato, E, Beckmann, M, Beeckman, H, Beierkuhnlein, C, Bekker, R, Belfry, G, Belluau, M, Beloiu, M, Benavides, R, Benomar, L, Berdugo-Lattke, ML, Berenguer, E, Bergamin, R, Bergmann, J, Berner, L, Bernhardt-Romermann, M, Bigler, C, Bjorkman, AD, Blackman, C, Blanco, C, Blonder, B, Blumenthal, D, Bocanegra-Gonzalez, KT, Boeckx, P, Bohlman, S, Bohning-Gaese, K, Boisvert-Marsh, L, Bond, W, Bond-Lamberty, B, Bonisch, G, Boom, A, Boonman, CCF, Bordin, K, Boughton, EH, Boukili, V, Bowman, DMJS, Bravo, S, Brendel, MR, Broadley, MR, Brown, KA, Bruelheide, H, Brumnich, F, Bruun, HH, Bruy, D, Buchanan, SW, Bucher, SF, Buchmann, N, Buitenwerf, R, Bunker, DE, Burger, J, Burrascano, S, Burslem, DFRP, Butterfield, BJ, Byun, C, Caccianiga, M, Cadotte, M, Cailleret, M, Camac, J, Camarero, JJ, Campany, C, Campetella, G, Campos, JA, Cano-Arboleda, L, Canullo, R, Carbognani, M, Carlucci, MB, Carvalho, F, Casanoves, F, Castagneyrol, B, Catford, JA, Cavender-Bares, J, Cerabolini, BEL, Cervellini, M, Chacon-Madrigal, E, Chapin, FS, Chapin, K, Chelli, S, Chen, AP, Chen, SC, Cherubini, P, Chianucci, F, Choat, B, Chung, KS, Chytry, M, Ciccarelli, D, Coll, L, Collins, CG, Conti, L, Coomes, D, Cornelissen, JHC, Cornwell, WK, Corona, P, Coyea, M, Craine, J, Craven, D, Cromsigt, JPGM, Csecserits, A, Cufar, K, Cuntz, M, da Silva, AC, Dahlin, KM, Dainese, M, Dalke, I, Dalle Fratte, M, Danihelka, J, Dannoura, M, Dawson, S, de Beer, AJ, de Dios, VR, De Frutos, A, de Gasper, AL, De Long, JR, Dechant, B, Delagrange, S, Delpierre, N, Derroire, G, Dias, AS, Diaz, S, Diaz-Toribio, MH, Dimitrakopoulos, PG, Dobrowolski, M, Doktor, D, Domingues, TF, Dong, N, Dransfield, J, Dressler, S, Drevojan, P, Duarte, L, Ducouret, E, Dullinger, S, Durka, W, Duursma, R, Dymova, O, E-Vojtko, A, Eckstein, RL, Ejtehadi, H, Elser, J, Emilio, T, Engemann, K, Erfanian, MB, Erfmeier, A, Esquivel-Muelbert, A, Esser, G, Estiarte, M, Fagan, WF, Fagundez, J, Falster, DS, Fan, Y, Fang, JY, Farris, E, Fazlioglu, F, Feng, YH, Fernandez-Mendez, F, Ferrara, C, Ferreira, J, Fidelis, A, Finegan, B, Firn, J, Flowers, TJ, Flynn, DFB, Fontana, V, Forey, E, Forgiarini, C, Francois, L, Frangipani, M, Frank, D, Frenette-Dussault, C, Freschet, GT, Fry, EL, Fyllas, NM, Gachet, S, Gallagher, R, Ganade, G, Ganga, F, Garcia-Palacios, P, Gargaglione, V, Garnier, E, Garrido, JL, Garvizu, GS, Gea-Izquierdo, G, Gibson, D, Gillison, AN, Giroldo, A, Glasenhardt, MC, Gleason, S, Gliesch, M, Goldberg, E, Goldel, B, Gonzalez-Akre, E, Gonzalez-Andujar, JL, Gonzalez-Melo, A, Gonzalez-Robles, A, Graae, BJ, Granda, E, Graves, S, Green, WA, Gregor, T, Gross, N, Guerin, GR, Gunther, A, Gutierrez, AG, Haddock, L, Haines, A, Hall, J, Hambuckers, A, Han, WX, Harrison, SP, Hattingh, W, Hawes, JE, He, PC, He, TH, Heberling, JM, Helm, A, Hempel, S, Hentschel, J, Herault, B, Heres, AM, Herz, K, Heuertz, M, Hickler, T, Hietz, P, Higuchi, P, Hipp, AL, Hirons, A, Hock, M, Hogan, JA, Holl, K, Honnay, O, Hornstein, D, Hou, EQ, Hough-Snee, N, Hovstad, KA, Ichie, T, Igic, B, Illa, E, Isaac, M, Ishihara, M, Ivanov, L, Ivanova, L, Iversen, CM, Izquierdo, J, Jackson, B, Jackson, RB, Jactel, H, Jagodzinski, AM, Jandt, U, Jansen, S, Jenkins, T, Jentsch, A, Jespersen, JRP, Jiang, GF, Johansen, JL, Johnson, D, Jokela, EJ, Joly, CA, Jordan, GJ, Joseph, GS, Junaedi, D, Junker, RR, Justes, E, Kabzems, R, Kane, J, Kaplan, Z, Kattenborn, T, Kattge, J, Kavelenova, L, Kearsley, E, Kempel, A, Kenzo, T, Kerkhoff, A, Khalil, MI, Kinlock, NL, Kissling, WD, Kitajima, K, Kitzberger, T, Kjoller, R, Klein, T, Kleyer, M, Klimesova, J, Klipel, J, Kloeppel, B, Klotz, S, Knops, JMH, Kohyama, T, Koike, F, Kollmann, J, Komac, B, Komatsu, K, Konig, C, Kraft, NJB, Kramer, K, Kreft, H, Kuhn, I, Kumarathunge, D, Kuppler, J, Kurokawa, H, Kurosawa, Y, Kuyah, S, Laclau, JP, Lafleur, B, Lallai, E, Lamb, E, Lamprecht, A, Larkin, DJ, Laughlin, D, Lavorel, S, Le Bagousse-Pinguet, Y, le Maire, G, le Roux, E, le Roux, PC, Leadley, P, Lee, T, Lens, F, Lewis, SL, Lhotsky, B, Li, XE, Li, YZ, Lichstein, JW, Liebergesell, M, Lim, JY, Lin, YS, Linares, JC, Liu, CJ, Liu, DJ, Liu, U, Livingstone, S, Llusia, J, Lohbeck, M, Lopez-Garcia, A, Lopez-Gonzalez, G, Lososova, Z, Louault, F, Lukacs, BA, Lukes, P, Luo, YJ, Lussu, M, Ma, SY, Mack, M, Maire, V, Makela, A, Makinen, H, Malhado, ACM, Mallik, A, Manning, P, Manzoni, S, Marchetti, Z, Marchino, L, Marcilio-Silva, V, Marcon, E, Marignani, M, Markesteijn, L, Marques, M, Martin, A, Martinez-Garza, C, Martinez-Vilalta, J, Maskova, T, Mason, K, Mason, N, Massad, TJ, Masse, J, Mayrose, I, Mazzochini, GG, McCarthy, J, McCormack, ML, McCulloh, K, McFadden, IR, McGill, BJ, McPartland, MY, Medeiros, JS, Medlyn, B, Meerts, P, Mehrabi, Z, Meir, P, Melo, FPL, Mencuccini, M, Meredieu, C, Messier, J, Meszaros, I, Metsaranta, J, Michaletz, ST, Michelaki, C, Migalina, S, Milla, R, Miller, JED, Minden, V, Ming, R, Mokany, K, Moles, AT, Molnar, VA, Molofsky, J, Molz, M, Montgomery, RA, Monty, A, Moravcova, L, Moreno-Martinez, A, Moretti, M, Mori, AS, Mori, S, Morris, D, Morrison, J, Mucina, L, Mueller, S, Muir, CD, Muller, SC, Munoz, F, Myers-Smith, IH, Myster, RW, Nagano, M, Naidu, S, Narayanan, A, Natesan, B, Negoita, L, Nelson, AS, Neuschulz, EL, Ni, J, Niedrist, G, Nieto, J, Niinemets, U, Nolan, R, Nottebrock, H, Nouvellon, Y, Novakovskiy, A, Nystuen, KO, O'Grady, A, O'Hara, K, O'Reilly-Nugent, A, Oakley, S, Oberhuber, W, Ohtsuka, T, Oliveira, R, Ollerer, K, Olson, ME, Onipchenko, V, Onoda, Y, Onstein, RE, Ordonez, JC, Osada, N, Ostonen, I, Ottaviani, G, Otto, S, Overbeck, GE, Ozinga, WA, Pahl, AT, Paine, CET, Pakeman, RJ, Papageorgiou, AC, Parfionova, E, Partel, M, Patacca, M, Paula, S, Paule, J, Pauli, H, Pausas, JG, Peco, B, Penuelas, J, Perea, A, Pereira, CMR, Peri, PL, Petisco-Souza, AC, Petraglia, A, Petritan, AM, Phillips, OL, Pierce, S, Pillar, VD, Pinho, BX, Pisek, J, Pomogaybin, A, Poorter, H, Portsmuth, A, Poschlod, P, Potvin, C, Pounds, D, Powell, AS, Power, SA, Prentice, IC, Prinzing, A, Puglielli, G, Pysek, P, Raevel, V, Rammig, A, Ransijn, J, Ray, CA, Reich, PB, Reichstein, M, Reid, DEB, Rejou-Mechain, M, Ribeiro, S, Richardson, S, Riibak, K, Rillig, MC, Riviera, F, Robert, EMR, Roberts, S, Robroek, B, Roddy, A, Rodrigues, AV, Rogers, A, Rollinson, E, Rolo, V, Romermann, C, Ronzhina, D, Roscher, C, Rosell, JA, Rosenfield, MF, Rossi, C, Roy, DB, Royer-Tardif, S, Ruger, N, Ruiz-Peinado, R, Rumpf, SB, Rusch, GM, Ryo, M, Sack, L, Saldana, A, Salgado-Negret, B, Salguero-Gomez, R, Santa-Regina, I, Santacruz-Garcia, AC, Santos, J, Sardans, J, Scalon, MC, Schamp, B, Scherer-Lorenzen, M, Schleuning, M, Schmid, B, Schmidt, M, Schmitt, S, Schneider, JV, Schowanek, SD, Schrader, J, Schrodt, F, Schuldt, B, Schurr, F, Semchenko, M, Seymour, C, Sfair, JC, Sharpe, JM, Sheppard, CS, Sheremetiev, S, Shiodera, S, Shipley, B, Shovon, TA, Siebenkas, A, Sierra, C, Silva, M, Silva, V, Sitzia, T, Sjoman, H, Slot, M, Smith, NG, Sodhi, D, Soltis, D, Soltis, P, Somers, B, Sonnier, G, Sorensen, MV, Sosinski, EE, Soudzilovskaia, NA, Souza, AF, Spasojevic, M, Sperandii, MG, Stan, AB, Stegen, J, Steinbauer, K, Stephan, JG, Sterck, F, Stojanovic, DB, Strydom, T, Suarez, ML, Svenning, JC, Svitkova, I, Svitok, M, Svoboda, M, Swaine, E, Swenson, N, Tabarelli, M, Takagi, K, Tappeiner, U, Tarifa, R, Tarin, T, Tautenhahn, S, Tauugourdeau, S, Tavsanoglu, C, te Beest, M, Tedersoo, L, Thiffault, N, Thom, D, Thomas, E, Thompson, K, Thornton, PE, Thuiller, W, Tichy, L, Tissue, D, Tjoelker, MG, Tng, DYP, Tobias, J, Torok, P, Torres-Ruiz, JM, Tothmeresz, B, Treurnicht, M, Trivellone, V, Trolliet, F, Trotsiuk, V, Tsakalos, JL, Tsiripidis, I, Tysklind, N, Umehara, T, Usoltsev, V. A., Vadeboncoeur, M, Vaezi, J, Valderrama, MY, Valladares, F, Vamosi, J, van Bodegom, PM, van Breugel, M, Van Cleemput, E, van de Weg, M, van der Merwe, S, van der Plas, F, van der Sande, MT, van Kleunen, M, Van Meerbeek, K, Vanderwel, M, Vanselow, KA, Varhammar, A, Varone, L, Vassilev, K, Vellend, M, Veneklaas, EJ, Verbeeck, H, Verheyen, K, Vibrans, A, Vieira, I, Villacis, J, Violle, C, Vivek, P, Wagner, K, Waldram, M, Waldron, A, Walker, AP, Waller, M, Walther, G, Wang, F, Wang, H, Wang, WQ, Watkins, H, Watkins, J, Weber, U, Weedon, JT, Wei, LP, Weigelt, P, Weiher, E, Wells, AW, Wellstein, C, Wenk, E, Werner, GDA, Westoby, M, Westwood, A, White, PJ, Whitten, M, Williams, M, Winkler, DE, Winter, K, Wirth, C, Womack, C, Wright, IJ, Wright, J, Wright, SJ, Ximenes, F, Yamada, T, Yamaji, K, Yanai, R, Yankov, N, Yguel, B, Zanini, KJ, Zanne, AE, Zeleny, D, Zhao, YP, Zheng, J, Zheng, JM, Zieminska, K, Zirbel, CR, Zizka, G, Zo-Bi, IC, Zotz, G +727 morecore 16S rDNA Profiling to Reveal the Influence of Seed-Applied Biostimulants on the Rhizosphere of Young Maize Plants [PDF]
, 2018 In an open field trial on two agricultural soils in NW Italy, the impact of two seed-applied biostimulants on the rhizosphere bacterial community of young maize plants was evaluated.Blandino, Massimo, DAL CORTIVO, Cristian, Maria Sanangelantoni, Anna, Vamerali, Teofilo, Visioli, Giovanna +4 morecore +2 more sourcesBridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme +8 morewiley +1 more source