Results 81 to 90 of about 316,072 (302)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Soil Biota as Drivers of Plant Community Assembly

open access: yes, 2018
Evidence is accumulating that belowground soil organisms are strong drivers of the aboveground plant community. In this chapter, we examine how soil communities influence plant community assembly through priority effects, soil legacy effects, and niche ...
Sveriges lantbruksuniversitet.   +1 more
core   +1 more source

Fungal social influencers: secondary metabolites as a platform for shaping the plant-associated community [PDF]

open access: yes, 2021
Fungal secondary metabolites (FSMs) are capable of manipulating plant community dynamics by inhibiting or facilitating the establishment of co-habitating organisms.
de Jonge, Ronnie   +3 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Microbial Population and Community Dynamics on Plant Roots and Their Feedbacks on Plant Communities [PDF]

open access: yesAnnual Review of Microbiology, 2012
The composition of the soil microbial community can be altered dramatically due to association with individual plant species, and these effects on the microbial community can have important feedbacks on plant ecology. Negative plant-soil feedback plays primary roles in maintaining plant community diversity, whereas positive plant-soil feedback may ...
James D, Bever   +2 more
openaire   +2 more sources

Plant Communities of the Tern Sanctuary on the Matsu Islands as a Breeding Habitat for Seabirds

open access: yesDiversity
The Matsu Islands Tern Refuge comprises eight reefs located at a relay station on the East Asian bird migration route, and it attracts many transiting, wintering, or breeding birds to inhabit and live on the reefs every year.
Wei Wang   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Ecology of palustrine wetlands in Lesotho: Vegetation classification, description and environmental factors

open access: yesKoedoe: African Protected Area Conservation and Science, 2019
The description and classification of wetland vegetation is important for water resource management and biodiversity conservation as it provides an understanding of the wetland vegetation–environment relationships and information to interpret spatial ...
Peter Chatanga, Erwin J.J. Sieben
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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