Results 41 to 50 of about 7,717,053 (332)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Anatomy, Flow Cytometry, and X-Ray Tomography Reveal Tissue Organization and Ploidy Distribution in Long-Term In Vitro Cultures of Melocactus Species

Frontiers in Plant Science, 2020
Cacti have a highly specialized stem that enables survival during extended dry periods. Despite the ornamental value of cacti and the fact that stems represent the main source of explants in tissue culture, there are no studies on their morpho-anatomical
Gabriela Torres-Silva, Elyabe Monteiro Matos, Ludmila Freitas Correia, Evandro Alexandre Fortini, Wellington Santos Soares, Diego Silva Batista, Caio Gomide Otoni, Aristéa Alves Azevedo, Lyderson Facio Viccini, Andréa Dias Koehler, Sheila Vitória Resende, Chelsea Dvorak Specht, Wagner Campos Otoni   +12 more
doaj   +1 more source

Determination of the Qualitative Composition of Biologically-Active Substances of Extracts of In Vitro Callus, Cell Suspension, and Root Cultures of the Medicinal Plant Rhodiola rosea [PDF]

, 2021
Lyudmila Asyakina, Станислав Сухих, Светлана Иванова, Alexander Prosekov, Elena Ulrikh, Evgeny Chupahin, Olga Babich   +6 more
openalex   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

In Vitro Propagation of Rheophytic Orchid, Epipactis flava Seidenf.—A Comparison of Semi-Solid, Continuous Immersion and Temporary Immersion Systems

Biology, 2019
Epipactis flava Seidenf. is an endangered Thai rheophytic orchid that has recently shown a rapid decrease in its natural habitat, prompting an urgent need for conservation using ex situ reintroduction methods.
Boworn Kunakhonnuruk, Phithak Inthima, Anupan Kongbangkerd   +2 more
doaj   +1 more source

Enhanced production of lupeol through elicitation in in vitro shoot cultures of snake grass (Clinacanthus nutans)

Notulae Scientia Biologicae, 2022
Clinacanthus nutans (Acanthaceae), generally known as ‘snake grass’, has diverse uses in customary system of herbal medicine. The species is endowed with various bioactive compounds exhibiting extensive pharmacological properties.
Somarajan L. CHIPPY, Vijayakumar T. ANJU VIJAY, Achuthan S. HEMANTHAKUMAR, Padmesh P. PILLAI, Thankappan S. PREETHA   +4 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

The homogenization of China's city flowers and city trees

People and Nature
Cultural homogeneity, similar to the loss biodiversity, is a significant global issue that is increasingly gaining attention. City flowers and city trees (CFTs) serve as emblematic cultural symbols of modern cities, often referred to as the ‘green ...
Zhuo Cheng, Ziyi Wu, Weizhe Chen, Wenxuan Li, Chen Lin, Qing Zhang, Chunlin Long   +6 more
doaj   +1 more source

The Effect of Blended Learning on Student's Learning Achievement and Science Process Skills in Plant Tissue Culture Course

International Journal of Instruction, 2019
The purpose of this research was to know the effect of blended learning strategy on learning achievement and science process skills of students in plant tissue culture course in the Universitas Negeri Medan. The research method was quasi experiment.
Fauziyah Harahap, N. E. A. Nasution, B. Manurung   +2 more
semanticscholar   +1 more source