Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin +14 more
wiley +1 more source
Adaptation of Plants to UV-B Radiation with Altitude in Tuha Basin: Synergistic Regulation of Epidermal Structure, Secondary Metabolites, and Organic Element Allocation. [PDF]
Wang XM +9 more
europepmc +1 more source
DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim +11 more
wiley +1 more source
Uptake and Translocation of Heavy Metals in Maize Leaves Exposed to Atmospheric Fallout. [PDF]
Wang Q +6 more
europepmc +1 more source
Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang +12 more
wiley +1 more source
The role, regulation and application of plant fruit trichomes. [PDF]
Fu Y +10 more
europepmc +1 more source
Roles of non-specific lipid transfer proteins in plant defense: structural and functional perspectives. [PDF]
McLaughlin JE, Tumer NE.
europepmc +1 more source
Ten new species of Lophodermium (Rhytismatales, Rhytismataceae) on pine needles in China. [PDF]
Wang SJ +6 more
europepmc +1 more source
Stacked scattering: The key to bright flowers lies in the mesophyll. [PDF]
De Paola L +5 more
europepmc +1 more source
Utilizing Lipid Bond Technology With Molecular Lipid Complex to Provide Lipid Treatment for Damaged Hair. [PDF]
Lai NH, Dang THN, Nguyen TT, Phan DTQ.
europepmc +1 more source

