Results 101 to 110 of about 1,325,312 (300)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Vegetation density as deduced from ERTS-1 MSS response [PDF]

Reflectance from vegetation increases with increasing vegetation density in the 0.75- to 1.35 micron wavelength interval. Therefore, ERTS-1 bands 6 (0.7 to 0.8 micron) and 7 (0.8 to 1.1 micron) contain information that should relate to the probable yield
Cuellar, J. A., Gausman, H. W., Gerbermann, A. H., Richardson, A. J., Wiegand, C. L.   +4 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Kesan baja Nitrogen dan kepadatan penanaman ke atas hasil biji Foxtail Millet [PDF]

, 1995
The objective of this study was to determine the effects of N fertilizer and plant density on grain yield production of foxtail millet (Setaria italica (Linn.) Beauv.).
Md. Kairudin, Narimah, Mohd Khamin, Nor Masitah   +1 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Optimizing the amount of irrigation water and plant density in the cultivation of median corn cultivar (SC500) using response surface method [PDF]

رویکردهای نوین در مهندسی آب و محیط زیست
This research was conducted using corn data collected from a research farm in Karaj city. The studied treatments included three levels of irrigation (I1, I2 and I3 based on 75, 100 and 125% of the crop’s water requirement, respectively) and three ...
Shokooh Karimi, Aslan Egdernezhad, Mohammad Mehdi Nakhjavanimoghaddam   +2 more
doaj   +1 more source

Physical characteristics of soil under different cropping and natural system on the plain of jars, Xieng Khouang province, Laos [PDF]

, 2006
Conservation agriculture and direct seeding mulch-based cropping (DMC) systems greatly modify plant and soil interaction. Plants commonly provide energy that fuels biological processes and either directly or indirectly creates structure within soils ...
Chabanne, André, Lienhard, Pascal, Saphanthong, Vilasack, Sosomphou, Thammakham, Séguy, Lucien, Tivet, Florent   +5 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source