Results 131 to 140 of about 5,470,722 (305)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Evaluating the Effects of Seeding Rate on Agronomic Traits of 'Katran' Chickpea (Cicer arietinum L.) Using Principal Component Analysis

ISPEC Journal of Agricultural Sciences
Establishing an optimal plant population is a critical factor for maximizing seed yield in chickpea (Cicer arietinum L.). This study was conducted to determine the influence of six seeding rates (100 to 350 kg ha⁻¹) on yield and its components in the ...
Zekeriya KARA , Cengiz YÜRÜRDURMAZ , Alihan ÇOKKIZGIN   +2 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Integrated transcriptomic and metabolomic analyses reveal optimized cultivation strategies for purple potatoes (Solanum tuberosum L.)

Frontiers in Plant Science
Potato (Solanum tuberosum L.), a cornerstone of global food security, faces significant yield limitations worldwide. Fertilization regimes and planting density critically determine potato yield and quality.
Weiran Zhong, Jin Yang, Fengming Liang, Qiang Ma   +3 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

APPLICATION OF PLANT GROWTH REGULATORS ON CORN CROPS IN THE SOUTHERN STEPPE OF UKRAINE

Меліорація і водне господарство
The aim of the research was to determine the productivity of the Ingulsky corn hybrid of the medium-ripening group of maturity depending on seed and plant treatment during the growing season when applying Regoplant and Vermystym biostimulants, as well as
P. V. Pysarenko, S. O. Zaiets, R. M. Vasylenko, Z. V. Shcherbyna   +3 more
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Grain yield and N uptake of maize in response to increased plant density under reduced water and nitrogen supply conditions

Journal of Integrative Agriculture
The development of modern agriculture requires the reduction of water and chemical N fertilizer inputs. Increasing the planting density can maintain higher yields, but also consumes more of these restrictive resources. However, whether an increased maize
Jingui Wei, Qiang Chai, Wen Yin, Hong Fan, Yao Guo, Falong Hu, Zhilong Fan, Qiming Wang   +7 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source