Results 201 to 210 of about 5,197,418 (291)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Plant Density and Location: Optimization of Growth and Quality of Cut Sunflower in Tropical and Subtropical Environments. [PDF]

Plants (Basel)
Tomasi TC, Reis LC, Taira TL, Soares JS, Tomiozzo R, Uhlmann LO, Streck NA, Sorgato JC.   +7 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The effects of plant density and duration of vegetative growth phase on agronomic traits of medicinal cannabis (Cannabis sativa L.): A regression analysis. [PDF]

PLoS One
Schober T, Präger A, Hartung J, Graeff-Hönninger S.   +3 more
europepmc   +1 more source

Effects of Intra- and Interspecific Plant Density on Rhizosphere Bacterial Communities. [PDF]

Front Microbiol, 2020
Cavalieri A, Bak F, Garcia-Lemos AM, Weiner J, Nicolaisen MH, Nybroe O.   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Impact of irrigation, nitrogen fertilization, and plant density on stay-green and its effects on agronomic traits in maize. [PDF]

Front Plant Sci
Chibane N, Revilla P, Yannam VRR, Marcet P, Covelo EF, Ordás B.   +5 more
europepmc   +1 more source

Marginal superiority of maize: an indicator for density tolerance under high plant density. [PDF]

Sci Rep, 2020
Liu G, Liu W, Yang Y, Guo X, Zhang G, Li J, Xie R, Ming B, Wang K, Hou P, Li S.   +10 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Phenology, growth, and seed tuber yield in potato (Solanum tuberosum L) varieties as influenced by plant density at adet, northwestern Ethiopia. [PDF]

Heliyon
Yayeh SG, Mohammed W, Woldetsadk K, Bezu T, Dessalegn Y, Asredie S.   +5 more
europepmc   +1 more source