Results 231 to 240 of about 11,906,005 (282)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

It takes a village: how plant-associated bacterial communities socialise to shape plant growth and health. [PDF]

Essays Biochem
Escudero-Martínez C, Tkacz A, Albareda M, Sánchez-Cañizares C.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A streamlined protocol for small-scale protoplast generation and CRISPR/Cpf1-mediated genome editing in <i>Fusarium oxysporum</i>. [PDF]

iScience
Zheng JZ, Huang SC, Zeng WT, Lin YH, Chang TH.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The Rise of Plant Pan-Genomes: From Genome Variation to Predictive Breeding. [PDF]

Adv Genet (Hoboken)
Peng D, Liao X, Tang L, Wu Z.
europepmc   +1 more source

Medium-adaptive wideband near-field antenna for microwave detection of internal cavities in plant stems. [PDF]

Sci Rep
Elkial MM, Hussein KFA, Mustafa M.
europepmc   +1 more source

Optimization of a bionic end-effector for automated cherry tomato harvesting using Response Surface Methodology and Box-Behnken design. [PDF]

PLoS One
Xie H, Miao Y, Zi Q, Kong D.
europepmc   +1 more source

Amended engineered soil promotes coordinated soil-plant-microbiome responses during early-stage slope restoration. [PDF]

Front Bioeng Biotechnol
Chen Z, Du Y, Li H, Wen X, Chen L, Wang W, Wu P.   +6 more
europepmc   +1 more source

Challenges and Future Directives of Synthetic Biology in Engineering Plant-Microbe Partnerships for Sustainable Agriculture. [PDF]

Biotechnol Bioeng
Enagbonma BJ, Molefe-Madlaliso RR, Adebayo AA, Oyedoh OP, Oribhabor GO, Shittu OE, Babalola OO.   +6 more
europepmc   +1 more source