Results 171 to 180 of about 635,909 (318)

Endogenous Circadian Rhythms in Plant Bioelectric Signals: Cross-Station Replication and Visitor-Driven Suppression in a Public Exhibition. [PDF]

Biomimetics (Basel)
Gloor PA.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

From "synthetic" to defined microbial communities for clearer terminology. [PDF]

Nat Commun
Koch H, Clavel T, Mayr C, Coltman BL, Schloter M, Vorholt JA, Sanz Y, Cernava T, Beattie GA, Lange L, Chaillou S, Kovács ÁT, Smidt H, Pieterse CMJ, Kostic T, Finkel OM, Lawson CE, Cocolin L, Mercado-Blanco J, Finn RD, Papadopoulou KK, Ryan M, Candela M, Cotter PD, Berg G, O'Sullivan O, Delgado-Baquerizo M, Trivedi P, Charles TC, Singh BK, Brader G, Marian M, Sessitsch A.   +32 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Molecular, Microbial, and Ecological Drivers of Duckweed Phytoremediation in Aquatic Environments. [PDF]

Biology (Basel)
Thingujam D, Malacrinò A, Pajerowska-Mukhtar KM, Mukhtar MS, Mukhtar MS.   +4 more
europepmc   +1 more source

Design and Construction of Molten Salt Parabolic Trough HPS Project in Évora, Portugal

, 2012
In the Portuguese city of Évora a parabolic salt loop is being constructed in order to demonstrate the viability of this system. Different partners have teamed-up for this task. Siemens takes the project lead in the German HPS consortium.
Wittmann, Michael, Ernst, Ralph, Stefan, Christian-Florin, Müller-Elvers, Christian, Schubert, Anne-Claire, Saur, Mirko, Übler, Matthias, Hillebrand, Stephan   +7 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

OpenMCT: an open-source DC motor control educational kit. [PDF]

HardwareX
Von Chong A, Vargas S, Duhé JF, Cárdenas D.   +3 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Advances in molecular breeding of medicinal plants. [PDF]

Mol Hortic
Wang Y, Jia X, Sun C, Chen W, Xiao Y.
europepmc   +1 more source