Results 111 to 120 of about 1,405,484 (345)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Downy mildew has been identified as the primary pathogen plaguing our northeastern hop yards. This disease causes reduced yield, poor hop quality, and can cause the plant to die in severe cases.
Cubins, Julija +3 more
core +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Heterogeneous microbial community associated with Bursaphelenchus xylophilus [PDF]
Pine wilt disease (PWD) is a complex disease integrating three major factors: the causal agent, the pinewood nematode Bursaphelenchus xylophilus; the insect-vector Monochamus spp.; and the host pine tree, Pinus sp.
Barbosa, Pedro +6 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Plant Disease and the Regulation of Enzymes Involved in Lignification [PDF]
Jean Collendavelloo +2 more
openalex +1 more source
Role of the whitefly maturation period on mosaic disease propagation in Jatropha curcas plant [PDF]
Fahad Al Basir
openalex +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Elevation in carbon dioxide is a global threat, driving anthropogenic climate change. How disease-vectoring mosquitoes respond to these changes is currently largely unknown.
Sukritha Nalikkaramal +2 more
doaj +1 more source
Mesenchymal stem cells (MSCs) can self-renew and differentiate into several lineages and can be isolated from different tissues such as bone marrow, adipose tissue, umbilical cord blood, and muscle.
Na-Yeon Gu +6 more
doaj +1 more source

