Results 111 to 120 of about 475,966 (276)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Plant Disease detection system

International Journal for Research in Applied Science and Engineering Technology
This project develops a Plant Leaf Disease Detection System that uses machine learning to identify plant diseases from uploaded leaf images. By applying a pre-trained deep learning model, the system provides real-time diagnosis and suggests remedies stored in a database.
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Plant Disease Detection from Images

, 2020
Plant disease detection is a huge problem and often require professional help to detect the disease. This research focuses on creating a deep learning model that detects the type of disease that affected the plant from the images of the leaves of the plants.
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Application of Non-Destructive Technology in Plant Disease Detection: Review

Agriculture
In recent years, research on plant disease detection has combined artificial intelligence, hyperspectral imaging, unmanned aerial vehicle remote sensing, and other technologies, promoting the transformation of pest and disease control in smart ...
Yanping Wang, Jun Sun, Zhaoqi Wu, Yilin Jia, Chunxia Dai   +4 more
doaj   +1 more source

Fungal community survey of Fraxinus excelior in New Zealand [PDF]

, 2012
The European Ash tree (Fraxinus excelsior) is widely grown throughout Europe. As a large deciduous tree species, it grows a tall, domed crown and has an attractive tree shape, so it is considered as a popular amenity tree species. European Ash is planted
Chen, Jie
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Ensuring Food Security and Biodiversity: A Novel Convolutional Neural Network (CNN) for Early Detection of Plant Disease in Precision Agriculture

Proceedings
Conventional disease detection methods in agriculture are constrained by the presence of personal opinions and the amount of work required, which hinder broad-scale disease monitoring.
Md Jiabul Hoque, Md. Saiful Islam, Mahadi Hassan, Mohammad Minhazul Islam   +3 more
doaj   +1 more source