Results 201 to 210 of about 4,341,163 (257)

Asynchrony and functional diversity couple herbivore community dynamics to host plant diversity. [PDF]

Nat Commun
Wang MQ, Albert G, Seifert CL, Chesters D, Bruelheide H, Li Y, Chen JT, Davrinche A, Haider S, Li S, von Oheimb G, Proß T, Ma K, Liu X, Luo A, Schuldt A, Zhu CD.   +16 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Environmental change shapes understory plant diversity and dominance in boreal forests. [PDF]

Nat Commun
Chen X, Reich PB, Chen X, Hisano M, Taylor AR, Li D, Chang SX.   +6 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Plant diversity influences plant volatile emission with varying effects at the species and community levels. [PDF]

Proc Natl Acad Sci U S A
Medina-van Berkum P, Albracht C, Bröcher M, Solbach MD, Stein G, Bonkowski M, Buscot F, Heintz-Buschart A, Ebeling A, Eisenhauer N, El-Madany TS, Huang Y, Kuebler K, Meyer ST, Gershenzon J, Unsicker SB.   +15 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Plant Diversity and Seasonal Variation Drive Animal Diversity and Community Structure in Eastern China. [PDF]

Animals (Basel)
Chen X, Jiang R, Chen Y, Yang R, He Y, Zou S, Ying J, Yi L, Ye Y, Peng S, Ge Z.   +10 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Species-specific dung characteristics and selective grazing jointly affect plant diversity in an experimental grassland community. [PDF]

Commun Biol
Sun X, Sitters J, Teixeira LH, Wassen MJ, Olde Venterink H.   +4 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source