Results 131 to 140 of about 4,323,457 (339)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Differential Effects of Increasing Salinity on Germination and Seedling Growth of Native and Exotic Invasive Cordgrasses [PDF]

open access: yes, 2019
Soil salinity is a key environmental factor influencing germination and seedling establishment in salt marshes. Global warming and sea level rise are changing estuarine salinity, and may modify the colonization ability of halophytes.
Castillo Segura, Jesús Manuel   +4 more
core   +2 more sources

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

The role of the testa during development and in establishment of dormancy of the legume seed

open access: yesFrontiers in Plant Science, 2014
Timing of seed germination is one of the key steps in plant life cycles. It determines the beginning of plant growth in natural or agricultural ecosystems.
Petr eSmýkal   +4 more
doaj   +1 more source

Plant Cellular and Molecular Biotechnology: Following Mariotti's Steps [PDF]

open access: yes, 2019
This review is dedicated to the memory of Prof. Domenico Mariotti, who significantly contributed to establishing the Italian research community in Agricultural Genetics and carried out the first experiments of Agrobacterium-mediated plant genetic ...
Caretto, Sofia   +11 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Yellow Nutsedge (Cyperus esculentus L.) as an Agricultural Crop in Brazil: Tuber Dormancy Breaking

open access: yesAgronomy
Yellow nutsedge (Cyperus esculentus L.) is cultivated worldwide due to its agricultural and biotechnological potential. In Brazil, it is considered a weed, and we lack studies on its cultivation. Overcoming tuber dormancy is crucial for propagation. This
Márcio Antônio Godoi Junior   +5 more
doaj   +1 more source

Network properties underlying seed germination control [PDF]

open access: yes, 2007
We sought to gain a mechanistic understanding of the control of seed dormancy and germination by hormone balance. The field has matured to a stage where most of the key genes are known, and competing hypotheses have been proposed to explain how hormone ...
Fozard, John, Penfield, Steven
core  

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Transcriptomic and Metabolomic Research on the Germination Process of Panax ginseng Overwintering Buds

open access: yesPlants
Ginseng (Panax ginseng C. A. Meyer) is a perennial plant with a long dormancy period. While some researchers employ gibberellin and other substances to stimulate premature germination, this method is limited to laboratory settings and cannot be applied ...
Ranqi Li   +6 more
doaj   +1 more source

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