Results 191 to 200 of about 112,483 (301)

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Island influences on plant functional traits and trait-trait associations across species- and community-scales. [PDF]

New Phytol
Song Y, McDowell NG, Zhang Z, Pivovaroff AL, Xu M, Ren W, He D, Yan ER, Delzon S.   +8 more
europepmc   +1 more source

How to Improve the Predictions of Plant Functional Traits on Ecosystem Functioning? [PDF]

Front Plant Sci, 2021
Liu C, Li Y, Yan P, He N.
europepmc   +1 more source

Functional analysis of secondary tropical dry forests in a region of the Colombia, Caribbean

, 2013
Secondary tropical forests are increasingly recognized for their role conserving biodiversity in agricultural landscapes and this role is especially important for seasonally dry tropical forests (SDTF), one of the most threatened tropical forested ...
Castellanos Castro, C
core  

Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine

Advanced Science, EarlyView.
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng, Lianzhu Zhou, Xinyue Fang, Ruoyan Zhao, Qi Xu, Mengrui Du, Ting Hou, Guizhou Huang, Yingchun Zhang, Sheng Yan, Ruo Yang, Zhongxin Jin, Yang Dong, Yanshuai Xu, Hua Xiao, Xiaodong Xu, Yi Liao, Xiping Wang, Yongfeng Zhou   +18 more
wiley   +1 more source

Plant Functional Traits and Diversity of Community Link to the Plant Invasion Dominance in the Subalpine Wetland of Shennongjia National Nature Reserve, China. [PDF]

Plants (Basel)
Zhang R, Xiong H, Liu Y, Xu Y, Huang L, Wen B, Zhao W, Zhao P, Xu B, Bai Y, Meng R.   +10 more
europepmc   +1 more source

Adaptation strategy of karst forests: Evidence from the community-weighted mean of plant functional traits. [PDF]

Ecol Evol, 2022
Liu L, Hu J, Chen X, Xu X, Yang Y, Ni J.
europepmc   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Plant Functional Traits or Microbiomes Associated with Diseases, Pests, Human Activities and Climate Change. [PDF]

Plants (Basel)
Guo JW, Yang H, Wang X.
europepmc   +1 more source

The impact of environmental and climatic variables on genetic diversity and plant functional traits of the endangered tuberous orchid (Orchis mascula L.). [PDF]

Sci Rep, 2022
Mafakheri M, Bakhshipour M, Omrani M, Gholizadeh H, Rahimi N, Mobaraki A, Rahimi M.   +6 more
europepmc   +1 more source