Results 231 to 240 of about 331,372 (300)

Plant functional traits are correlated with species persistence in the herb layer of old-growth beech forests. [PDF]

Sci Rep, 2020
Campetella G, Chelli S, Simonetti E, Damiani C, Bartha S, Wellstein C, Giorgini D, Puletti N, Mucina L, Cervellini M, Canullo R.   +10 more
europepmc   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Variation in plant functional traits explains the substitution distribution and allocation strategy of Stipa species across natural grasslands of Ningxia, Northern China. [PDF]

Ecol Evol
Yang J, Li X, Yang J, Yu S, Zhang H, Yang B.   +5 more
europepmc   +1 more source

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

Advanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun, Xu Yang, Wenchao Jiang, Chengbo Ji, Yingying Wu, Haoyu Sun, Xinyou Liu, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Junjie Zhao, Yuanyuan Ruan, Haojie Li, Xuefei Wang   +13 more
wiley   +1 more source

Local adaptation to climate inferred from intraspecific variation in plant functional traits along a latitudinal gradient. [PDF]

Conserv Physiol
Tudor EP, Lewandrowski W, Krauss S, Veneklaas EJ.   +3 more
europepmc   +1 more source

Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine

Advanced Science, EarlyView.
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng, Lianzhu Zhou, Xinyue Fang, Ruoyan Zhao, Qi Xu, Mengrui Du, Ting Hou, Guizhou Huang, Yingchun Zhang, Sheng Yan, Ruo Yang, Zhongxin Jin, Yang Dong, Yanshuai Xu, Hua Xiao, Xiaodong Xu, Yi Liao, Xiping Wang, Yongfeng Zhou   +18 more
wiley   +1 more source

Nitrogen Addition and Heterotroph Exclusion Affected Plant Species Diversity-Biomass Relationship by Affecting Plant Functional Traits. [PDF]

Plants (Basel)
Xu X, Yang L, Shen K, Cao H, Lin Y, Liu J, Han W.   +6 more
europepmc   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

Advanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng   +11 more
wiley   +1 more source

Effects of γ-polyglutamic acid on grassland sandy soil properties and plant functional traits exposed to drought stress. [PDF]

Sci Rep
Skalski T, Zając E, Jędrszczyk E, Papaj K, Kohyt J, Góra A, Kasprzycka A, Shytum D, Skowera B, Ziernicka-Wojtaszek A.   +9 more
europepmc   +1 more source

Plant functional traits differ in adaptability and are predicted to be differentially affected by climate change. [PDF]

Ecol Evol, 2020
Ahrens CW, Andrew ME, Mazanec RA, Ruthrof KX, Challis A, Hardy G, Byrne M, Tissue DT, Rymer PD.   +8 more
europepmc   +1 more source