Results 51 to 60 of about 98,248 (254)

Functional turnover from lowland to montane forests: evidence from the Hyrcanian forest in northern Iran

iForest - Biogeosciences and Forestry, 2015
Plant functional traits and functional diversity play key roles in ecosystem functioning. Exploring patterns of functional diversity is of great importance in the management process of forest ecosystems.
Jafari Seyed M, Zarre S, Alavipanah Seyed K, Ghahremaninejad F   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Joint multivariate and functional modeling for plant traits and reflectances

Environmental and Ecological Statistics, 2023
The investigation of leaf-level traits in response to varying environmental conditions has immense importance for understanding plant ecology. Remote sensing technology enables measurement of the reflectance of plants to make inferences about underlying traits along environmental gradients.
White, Philip A., Christensen, Michael F., Frye, Henry, Gelfand, Alan E., Silander Jr, John A.   +4 more
openaire   +2 more sources

Species prefer to shifting niche positions rather than expanding niche breadth to adapt to the heterogeneous karst forests

Forest Ecosystems
The interspecific variations of plant functional traits can characterize the niche positions of species within communities, while the intraspecific variations can accurately display the species’ niche breadth.
Shiren Chen, Zeyu Yang, Yuhang Wu, Yong Li, Longchenxi Meng, Luyao Chen, Yingqun Chen, Xuerong Shao, Mingzhen Sui, Guangqi Zhang, Danmei Chen, Yuejun He, Lipeng Zang, Qingfu Liu   +13 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Variation in leaf morphological, stomatal, and anatomical traits and their relationships in temperate and subtropical forests

Scientific Reports, 2019
Leaf functional traits have attracted the attention of ecologists for several decades, but few studies have systematically assessed leaf morphological traits (termed “economic traits”), stomatal (termed “hydraulic”), and anatomical traits of entire ...
Congcong Liu, Ying Li, Li Xu, Zhi Chen, Nianpeng He   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mycorrhizal fungal and tree root functional traits: Strategies for integration and future directions

Ecosphere, 2023
Plant functional traits offer ecologists quantifiable characteristics that may be used to determine the underlying mechanisms and drivers of processes at scales ranging from individual plants to entire ecosystems. While research on belowground functional
Samuel A. Z. Schaffer‐Morrison, Donald R. Zak   +1 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source