Results 101 to 110 of about 7,700,767 (289)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
, 1975 http://babel.hathitrust.org/cgi/pt?id=mdp.39015007427209;view=2up;ui=fullscreen#page/n0/mode ...
Symposium on Craniofacial Growth
core +3 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
, 1976 http://babel.hathitrust.org/cgi/pt?id=mdp.39015006456928;view=2up;ui=fullscreen#page/n0/mode ...
Symposium on Craniofacial Growth
core +2 more sources
, 2006 Nd3+, La3+ and Ce3+ at proper concentrations had positive effects on the cell growth of Arnebia euchroma and production of shikonin derivatives. A mixture of rare earth elements (MRE, La2O3:CeO2:Pr6O11: Sm2O3 = 255:175:3:1, mol/mol) behaved the most ...
Zhao, B, Ge, F, Wang, XD, Wang, YC
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Remote SensingTimely monitoring of cotton defoliation progress is crucial for optimizing the quality of mechanical harvesting. To accurately assess the defoliation status prior to mechanical picking, a field experiment was conducted in Hejian, Hebei Province, China ...
Yukun Wang +12 more
doaj +1 more source