Results 171 to 180 of about 115,294 (265)

From signals to solutions: stress-induced leaf senescence and synthetic biology and AI approaches for crop resilience. [PDF]

Mol Hortic
Ren SN, Zhu CY, Wang YQ, Bu T, Li Z, Yin W, Xia X, Wang HL.   +7 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The Transcriptional Regulator Crt1 is Involved in The Pathogenic Lifestyle of <i>Xanthomonas campestris</i> pv. <i>campestris</i> B100. [PDF]

Pol J Microbiol
Korszańska A, Lutter P, Ortseifen V, Pühler A, Niehaus K.   +4 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Effects of Rootstock and Exogenous Plant Growth Regulators on Volatile Aroma Profiles and Terpenoid-Mediated Defense in Table Grape Fruit. [PDF]

Life (Basel)
Zhao Y, Xu T, Hu L, Guo Y, Chen Z, Wu Y, Yang Z.   +6 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Characterization of an AsnC/Lrp-family transcriptional regulator in <i>Herbaspirillum rubrisubalbicans</i> M1: linking plant interaction, nitrogen response and PHB metabolism. [PDF]

Front Microbiol
Chaves RBR, Alves LPS, de Lima Nichio BT, Tuleski TR, Baura VA, Muller-Santos M, Tomazini E, Sampaio A, Souza EM, Monteiro RA.   +9 more
europepmc   +1 more source

Prohexadione, a plant growth regulator, inhibits histone lysine demethylases and modulates epigenetics. [PDF]

Toxicol Rep, 2014
Vavilala DT, Reddy S, Sachchidanand, Prakash S, Ponnaluri VKC, Kumar A, Mukherji M.   +6 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Explant origin and growth regulators as determinants of callus performance and terpenoid indole alkaloid accumulation in Catharanthus roseus. [PDF]

BMC Plant Biol
Desouky AF, El-Assal SE, Abdelsamad A, Reda AS, Danial N, Hanafy MS.   +5 more
europepmc   +1 more source