Results 241 to 250 of about 301,704 (359)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Amelioration of lodging in barley (Hordeum vulgare) using plant growth regulators

, 2020
SUDESH KUMAR, Malu Ram Yadav, K. C. Gupta, RANI SAXENA, Om Prakash Meena, Jogendra Singh, S. S. Rajput, K C Yadav, A S KHRUB   +8 more
openalex   +2 more sources

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

The Transcriptional Regulator Crt1 is Involved in The Pathogenic Lifestyle of <i>Xanthomonas campestris</i> pv. <i>campestris</i> B100. [PDF]

Pol J Microbiol
Korszańska A, Lutter P, Ortseifen V, Pühler A, Niehaus K.   +4 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Explant origin and growth regulators as determinants of callus performance and terpenoid indole alkaloid accumulation in Catharanthus roseus. [PDF]

BMC Plant Biol
Desouky AF, El-Assal SE, Abdelsamad A, Reda AS, Danial N, Hanafy MS.   +5 more
europepmc   +1 more source

Variation in biochemical and antioxidant attributes of Raphanus sativus in response to foliar application of plant leaf extracts as plant growth regulator. [PDF]

J Genet Eng Biotechnol, 2016
Ashraf R, Sultana B, Iqbal M, Mushtaq M.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Fertilization is more effective in alleviating yield loss of waterlogged crops than exogenous growth regulators: a meta-analysis. [PDF]

Front Plant Sci
Xu H, Jin DD, Wang YW, Liu GH, Zhao TY, Liu C, Tian LX.   +6 more
europepmc   +1 more source

Effect of plant growth regulators and type of explant on phenolic production from strawberry plant in vivo and in vitro.

, 2018
Ahmed Abbas Obaid, Wessam Malek Dawood, E. K. Al-Azawy   +2 more
openalex   +1 more source