Advanced Science, EarlyView.This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
Advanced Science, EarlyView.CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian +12 more
wiley +1 more source
Plant Hormone Pathway Is Involved in Regulating the Embryo Development Mechanism of the Hydrangea macrophylla Hybrid. [PDF]
Int J Mol SciZhu Y +6 more
europepmc +1 more source
Mathematical modeling of plant cell fate transitions controlled by hormonal signals
, 2020 Filip Z. Klawe +5 more
openalex +2 more sources
Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation
Advanced Science, EarlyView.BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang +13 more
wiley +1 more source
Seed Priming with 2,4-Epibrassionolide Enhances Seed Germination and Heat Tolerance in Rice by Regulating the Antioxidant System and Plant Hormone Signaling Pathways. [PDF]
Antioxidants (Basel)Qian J, Mo X, Wang Y, Li Q.
europepmc +1 more source
Plant Signaling Hormones and Transcription Factors: Key Regulators of Plant Responses to Growth, Development, and Stress [PDF]
Ayomi S. Thilakarathne +2 more
openalex +1 more source
Advanced Science, EarlyView.This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen +31 more
wiley +1 more source
Four MES genes from calamondin (Citrofortunella microcarpa) regulated citrus bacterial canker resistance through the plant hormone pathway. [PDF]
Front Plant SciXiao YX +6 more
europepmc +1 more source