Results 211 to 220 of about 99,221 (294)

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Role of <i>Rhizophagus intraradices</i> in Mitigating Salt Stress of <i>Sulla carnosa</i> Through Modulating Plant Hormones (ABA, SA, and JA) and Nutrient Profile. [PDF]

Biology (Basel)
Hidri R, Zorrig W, Debez A, Mahmoud OM, Zamarreño AM, García-Mina JM, Nait Mohamed S, Abdelly C, Azcon R, Aroca R.   +9 more
europepmc   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Human Skin Fibroblasts as an In Vitro Model Illustrating Changes in Collagen Levels and Skin Cell Migration Under the Influence of Selected Plant Hormones. [PDF]

Bioengineering (Basel)
Jabłońska-Trypuć A, Pankiewicz W, Wołejko E, Sokołowska G, Estévez J, Sogorb MA, Wydro U.   +6 more
europepmc   +1 more source

Tailored biosynthesis of gibberellin plant hormones in yeast.

Metab Eng, 2021
Kildegaard KR, Arnesen JA, Adiego-Pérez B, Rago D, Kristensen M, Klitgaard AK, Hansen EH, Hansen J, Borodina I.   +8 more
europepmc   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Occurrence of plant hormones in composts made from organic fraction of agri-food industry waste. [PDF]

Sci Rep
Sienkiewicz A, Krasowska M, Kowczyk-Sadowy M, Obidziński S, Piotrowska-Niczyporuk A, Bajguz A.   +5 more
europepmc   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Genome-Wide Analysis and Expression Profiling of Soybean RbcS Family in Response to Plant Hormones and Functional Identification of GmRbcS8 in Soybean Mosaic Virus. [PDF]

Int J Mol Sci
Zhou F, Feng W, Mou K, Yu Z, Zeng Y, Zhang W, Zhou Y, Li Y, Gao H, Xu K, Feng C, Jing Y, Li H.   +12 more
europepmc   +1 more source

Chitosan Induces Plant Hormones and Defenses in Tomato Root Exudates. [PDF]

Front Plant Sci, 2020
Suarez-Fernandez M, Marhuenda-Egea FC, Lopez-Moya F, Arnao MB, Cabrera-Escribano F, Nueda MJ, Gunsé B, Lopez-Llorca LV.   +7 more
europepmc   +1 more source